ADAMA MAKHTESHIM LTD.

The present invention provides a process for preparing the compound 5-fluoro-4-imine-3-methyl-1-(phenyl-4-sulfonyl)-3,4-dihydro-1H-pyrimidin-2-one having the formula (I): comprising (a) reacting 5-fluorocytosine with compound having the formula (III): in the presence of at least one polar solvent and at least one base to obtain the compound having the formula (II) and (b) reacting compound having the formula (II) with dimethylsulphate (DMS), wherein R is hydrogen, alkyl, alkenyl, alkynyl, alkoxy, haloalkyl, haloalkoxy, alkylthio, haloalkylthio, amino, alkylamino, dialkylamino, alkoxycarbonyl, alkyl carbonyl, hydroxyalkyl, ester, acid halogen, —SH, —OH, —NH 2 , —NO 2 , —CN or CF 3 , and X is a halogen or —OSO 2 PhR.

The present invention relates to efficient methods of controlling insects by applying novel combinations of active compounds comprising, Novaluron and at least one further active compound in a range of effective weight ratios of the active compounds, thereby controlling the said insects.

The present subject matter relates to seed treatment formulations comprising fluensulfone, their processes of preparation and methods of use.

A fungicidal oil liquid formulation comprising: a) at least one dithiocarbamate fungicide; b) at least one co-fungicide selected from the group consisting of triazole fungicides and strobilurin fungicides; and c) an agrochemically acceptable non-aqueous liquid carrier; wherein the dithiocarbamate fungicide is suspended in the liquid carrier; wherein the triazole fungicide and the strobilurin fungicide are dissolved in the liquid carrier; and wherein the liquid carrier optionally comprises an adjuvant.

The present invention provides a process for preparing a compound having the formula (I): wherein R is alkyl or alkylaryl; each of X 1 , X 2 , X 3 , X 4 and X 5 is, independently, H, alkyl, alkenyl, alkynyl, alkoxy, haloalkyl, haloalkoxy, alkylthio, haloalkylthio, amino, alkylamino, dialkylamino, alkoxycarbonyl, alkyl carbonyl, hydroxyalkyl, ester, acid halogen, —SH, —OH, —NH 2 , —NO 2 , —CN or CF 3 ; Y is O or S; and and Z is a halogen.

The present invention provides a combination comprising an amount of a keto-enol insecticide and an amount of a compound having the formula (I): R1-O—(CmH2mO)x-(CnH2nO)y-H wherein R1 is linear or branched, saturated or unsaturated acyl radical having from 14 to 20 carbon atoms; m is an integer equal to 2, n is an integer equal to 3, x is an integer of from 1 to 50 and y is an integer of from 0 to 50.

The invention relates to novel agrochemical compositions comprising: a) at least one triazole fungicide; b) carbonyl containing solvent; and c) N-alkyl pyrrolidone of formula (I) wherein R1 is a straight or branched, saturated or unsaturated, substituted or unsubstituted hydrocarbon group having from 5 to 10 carbon atoms. The invention also relates to the use of a combination of the abovementioned N-alkyl pyrrolidone of formula (I) with a carbonyl containing solvent for increasing the efficacy of one or more triazole fungicide. The invention further relates to an agrochemical composition comprising: a) at least one triazole fungicide; b) a carbonyl containing solvent; c) N-alkyl pyrrolidone of formula (I) and d) an effective amount of compound of formula (II) wherein R2 is linear or branched, saturated or unsaturated alkyl radical having from 14 to 20 carbon atoms; or R2 is linear or branched, saturated or unsaturated acyl radical having from 14 to 20 carbon atoms; or any combination thereof, Z is selected from oxygen or nitrogen atom, m is an integer equal to 2, n is an integer equal to 3, x is an integer of from 3 to 50 and y is an integer of from 0 to 50. The invention relates to the use of a compound of formula (II) for increasing the efficacy of one or more triazole fungicide; and to a method of treating plants or plant parts with a combination of one or more triazole(s) fungicide with compound of formula wherein the compound of formula (II) is for increasing the efficacy of the one or more triazole(s).

The present invention relates to the preparation of cyantraniliprole, comprising the preparation of 8-methyl-2,4-dioxo-1,4-dihydro-2H-benzo[d][1,3]oxazine-6-carbonitrile key intermediate via 2-amino-5-((hydroxyimino)methyl)-3-methylbenzoic acid. Wherein hydroxylamine attacks a benzylic formyl group, to obtain the 2-amino-5-((hydroxyimino)methyl)-3-methylbenzoic acid, that undergoes simultaneously or by consecutive steps dehydrogenation and cyclization to obtain the benzo[d][1,3]oxazine group and the cyano group of the desired product. In addition, an improved method for the synthesis of the benzylic formyl group is also displayed.

The invention relates to novel agrochemical compositions comprising: a) at least one triazole fungicide; b) carbonyl containing solvent; and c) N-alkyl pyrrolidone of formula (I) wherein R1 is a straight or branched, saturated or unsaturated, substituted or unsubstituted hydrocarbon group having from 5 to 10 carbon atoms. The invention also relates to the use of a combination of the abovementioned N-alkyl pyrrolidone of formula (I) with a carbonyl containing solvent for increasing the efficacy of one or more triazole fungicide. The invention further relates to an agrochemical composition comprising: a) at least one triazole fungicide; b) a carbonyl containing solvent; c) N-alkyl pyrrolidone of formula (I) and d) an effective amount of compound of formula (II) wherein R2 is linear or branched, saturated or unsaturated alkyl radical having from 14 to 20 carbon atoms; or R2 is linear or branched, saturated or unsaturated acyl radical having from 14 to 20 carbon atoms; or any combination thereof, Z is selected from oxygen or nitrogen atom, m is an integer equal to 2, n is an integer equal to 3, x is an integer of from 3 to 50 and y is an integer of from 0 to 50. The invention relates to the use of a compound of formula (II) for increasing the efficacy of one or more triazole fungicide; and to a method of treating plants or plant parts with a combination of one or more triazole(s) fungicide with compound of formula wherein the compound of formula (II) is for increasing the efficacy of the one or more triazole(s).

A composition of stereoisomers of sulfoxaflor, where these stereoisomers are selected from diastereomers A and B at a selected A:B ratio, are provided as a mixture of crystal structures, and are water soluble with water solubility of at least about 0.7±0.07 mg/ml, methods for preparing them and insecticides and/or pesticides preparations comprising them.