UnfoldIPThemes

Company patents

Arbor Biotechnologies, Inc.

Arbor Biotechnologies, Inc. shows a surprising shift in its patent strategy, with a significant decline across its core pharma_biotech categories. For instance, 'Pharmaceutical Preparations' saw a -57.1% YoY drop in 2024 and a -66.7% drop in 2025, while 'Therapeutic Activity (Pharma)' experienced a -100.0% YoY decline in 2026 so far, indicating a potential reprioritization away from these areas despite their foundational role in biotechnology.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

65 US filings (since 2023) · 4 categories · 4 themes

CRISPR-based Nucleic Acid Detection

Assays leveraging CRISPR-Cas systems (e.g., Cas12, Cas13) for highly specific and sensitive detection of target nucleic acids, often involving collateral cleavage activity or reporter molecules.

Genetic & Microbiological Assays
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64since 2023
-66.7%YoY
Nucleic Acid-Based Therapies

Therapeutic strategies employing nucleic acids (DNA, RNA, oligonucleotides) to modulate gene expression, deliver genetic material, or interfere with disease-causing pathways. Includes gene therapy using viral vectors.

Pharmaceutical PreparationsTherapeutic Activity (Pharma)
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44since 2023
-60.0%YoY
Advanced Cell & Gene Therapies

Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.

Pharmaceutical PreparationsPeptides & Proteins
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24since 2023
-50.0%YoY
Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
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5since 2023
n/a

Patents

Showing 1-10 of 85

Page 1 of 9
US 12655421 B2GRANTED
C12N15/11

CRISPR DNA targeting enzymes and systems

Filed:2020-09-14Pub:2026-06-16
Applicant:ARBOR BIOTECHNOLOGIES, INC.

The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.

US 12655404 B2GRANTED
C12N9/22

CRISPR DNA targeting enzymes and systems

Filed:2020-07-10Pub:2026-06-16
Applicant:ARBOR BIOTECHNOLOGIES, INC.

The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.

US 12553045 B2GRANTED
C12N15/11

Crispr DNA targeting enzymes and systems

Filed:2018-12-28Pub:2026-02-17
Applicant:ARBOR BIOTECHNOLOGIES, INC.

The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR-Cas systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.

US 12522812 B2GRANTED
C12N9/22

CRISPR-associated systems and components

Filed:2019-05-16Pub:2026-01-13
Applicant:ARBOR BIOTECHNOLOGIES, INC.

The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of DNA, RNA, and protein substrates. Each system includes one or more protein components and one or more nucleic acid components that together target DNA, RNA, or protein substrates.

US 12460203 B2GRANTED
C12N15/11

CRISPR RNA targeting enzymes and systems and uses thereof

Filed:2021-11-08Pub:2025-11-04
Applicant:Arbor Biotechnologies, Inc.

The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of a nucleic acid.

US 12460190 B2GRANTED
C12N9/22

CRISPR DNA targeting enzymes and systems

Filed:2020-09-09Pub:2025-11-04
Applicant:ARBOR BIOTECHNOLOGIES, INC.

The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.

US 20250290053 A1APPLICATION
C12N9/22

COMPOSITIONS COMPRISING A CRISPR NUCLEASE AND USES THEREOF

Filed:2025-05-30Pub:2025-09-18
Applicant:Arbor Biotechnologies, Inc.

The present disclosure relates to variant polypeptides, methods of preparing the variant polypeptides, processes for characterizing the variant polypeptides, compositions and cells comprising the variant polypeptides, and methods of using the variant polypeptides. The disclosure further relates to complexes comprising the variant polypeptides, methods of producing the complexes, processes for characterizing the complexes, cells comprising the complexes, and methods of using the complexes.

US 20250243511 A1APPLICATION
C12N15/90

CRISPR-ASSOCIATED TRANSPOSON SYSTEMS AND METHODS OF USING SAME

Filed:2025-01-17Pub:2025-07-31
Applicant:Arbor Biotechnologies, Inc.

The present disclosure relates to systems, compositions and methods for modifying target nucleic acid sequences.

US 12344870 B2GRANTED
C12N9/22

Compositions comprising a CRISPR nuclease and uses thereof

Filed:2022-09-08Pub:2025-07-01
Applicant:Arbor Biotechnologies, Inc.

The present disclosure relates to variant polypeptides, methods of preparing the variant polypeptides, processes for characterizing the variant polypeptides, compositions and cells comprising the variant polypeptides, and methods of using the variant polypeptides. The disclosure further relates to complexes comprising the variant polypeptides, methods of producing the complexes, processes for characterizing the complexes, cells comprising the complexes, and methods of using the complexes.

US 20250154483 A1APPLICATION
C12N9/22

NOVEL CRISPR DNA AND RNA TARGETING ENZYMES AND SYSTEMS

Filed:2024-11-20Pub:2025-05-15
Applicant:Arbor Biotechnologies, Inc.

The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.

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