ARKRAY, Inc.

An electrophoresis unit including: a capillary flow path (CFP) through which a sample solution (SS) moves when the CFP is filled with a running solution (RS); a pair of electrodes installed near both ends of the CFP; a detector provided at an intermediate part of the CFP; a first flow path (FFP) and a second flow path (SFP) communicating with the both sides of the CFP, respectively; a first supply source (FSS) supplying the SS to the FFP; a second supply source (SSS) supplying the RS to the SFP; a pump moving the RS from the SSS to the SFP and moving the SS from the FSS to the FFP; a first auxiliary supply source supplying insulating fluid to the FFP; a second auxiliary supply source supplying insulating fluid to the SFP; and a switch switching a fluid path of fluid supplied to the FFP and the SFP.

An electrophoresis unit, having: a first flow path including a first liquid reservoir, a first inflow path at which a solution flows into the first liquid reservoir, a first outflow path at which the solution flows out from the first liquid reservoir, and a first liquid level adjustment section open to an exterior; a second flow path including a second liquid reservoir, a second inflow path at which the solution flows into the second liquid reservoir, a second outflow path at which the solution flows out from the second liquid reservoir, and a second liquid level adjustment section open to the exterior; a capillary that leads from the first liquid reservoir to the second liquid reservoir; and an electrode arranged at respective interiors of the first and the second flow paths. Vertical direction positions of the first and the second liquid level adjustment sections are equal to each other.

There is provided a method of feeding a sample liquid to a flow cell having a merging path in which a sample liquid and a sheath liquid flow, at least one sheath liquid flow path that introduces the sheath liquid into the merging path along a flowing direction of fluid in the merging path, and a sample flow path introducing the sample liquid into the merging path at an angle orthogonal to the flowing direction, wherein, given that an opening surface area of a sheath liquid introducing opening of the sheath liquid flow path onto the merging path is S1, an opening surface area of a sample liquid introducing opening of the sample flow path onto the merging path is S2, a flow rate per unit time of the sheath liquid supplied to the sheath liquid flow path is L, and a flow rate per unit time of the sample liquid supplied to the sample flow path is J, a relationship (L/S1)/(J/S2)≥0.7 is satisfied.

An analysis device that includes a placement section, a pressing member, and a measurement member, has an analysis kit including a chip provided with a capillary through which a sample flows and a cartridge superimposed on the chip, and in which a liquid reservoir placed therein to enable a component present in sample can be measured in a state in which the chip and the cartridge have been fitted together. The analysis kit is placed on the placement section. The pressing member presses the analysis kit in a direction in which the cartridge is superimposed on the chip to sandwich the analysis kit between the pressing member and the placement section, and to fit the chip and the cartridge together. The measurement member that measures the component present in the sample in the analysis kit in which the chip and the cartridge have been fitted together.

An analysis method using a microchip which is provided with a capillary flow path, and a sample reservoir connected to the capillary flow path, in which the capillary flow path is filled with a first liquid for electrophoresis, and a second liquid containing a sample is stored in the sample reservoir, and including a pressurization process in which the first liquid is pressurized into the capillary flow path from a side of the capillary flow path that is opposite from the side connected to the sample reservoir, and a separation process in which a voltage is applied between the sample reservoir storing the second liquid and the capillary flow path filled with the first liquid, such that components in the sample contained in the second liquid move in the capillary flow path and the components are separated in the capillary flow path.

The present disclosure provides an analysis chip device used in capillary electrophoresis.

A liquid sample analysis method including communicating a specific flow path with an aspirator via a branch flow path, aspirating air from the aspirator, aspirating a liquid sample into the sample supply path from the aspirator so that an entire amount of the aspirated air is accommodated in the branch flow path, communicating a sample extrusion path with a sample port, communicating a sheath fluid supply path with a sheath fluid port, and isolating the branch flow path from both the sample supply path and the specific flow path, extruding the liquid sample in the sample supply path so as to inflow into the sample flow path by causing a sheath fluid to inflow into the sheath fluid flow path from the sheath fluid supply path and causing the sheath fluid to inflow into the sample supply path from the sample extrusion path.