Company patents
Assistance Publique - Hopitaux de Paris
Assistance Publique - Hopitaux de Paris, despite its core focus on "Pharmaceutical Preparations" (46.1% of portfolio) and "Therapeutic Activity (Pharma)" (30.5%), shows a surprising shift away from these areas with significant declines in 2025 and so far in 2026 (e.g., "Pharmaceutical Preparations" declined by 40.9% in 2025 and 53.8% so far in 2026). While most categories saw a decline in 2025, the sustained growth in "Genetic & Microbiological Assays" (YoY +50.0% so far in 2026) suggests an emerging focus on advanced diagnostic and research tools, contrasting with the general slowdown across its traditional pharma and medical device patenting.
Patent Trend by Technology Area
Yearly patent publications since 2023
Product themes
Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.
128 US filings (since 2023) · 12 categories · 22 themes
Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.
Therapeutic approaches involving the use of living cells, often genetically modified or ex vivo activated, to treat diseases, particularly cancer, by modulating immune responses or replacing damaged cells.
Design and engineering of proteins or peptides to directly modulate immune responses, including enhancing antigen presentation, suppressing inflammation, or activating specific immune cell types.
Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.
Identification and measurement of specific nucleic acid sequences (DNA, RNA), their expression levels, or epigenetic modifications (e.g., methylation) as indicators for disease presence, progression, risk, or treatment response.
Therapeutic strategies employing nucleic acids (DNA, RNA, oligonucleotides) to modulate gene expression, deliver genetic material, or interfere with disease-causing pathways. Includes gene therapy using viral vectors.
Design and application of devices that are inserted into the body or implanted to treat diseases, modulate physiological functions, or repair anatomical structures.
Techniques for identifying microorganisms, assessing their viability, quantifying their presence, profiling their metabolic activity, or determining their susceptibility to antimicrobial agents, often in complex biological or environmental samples.
Therapeutic interventions that target immune checkpoint pathways to either enhance or suppress immune responses, often used in cancer immunotherapy or autoimmune diseases.
Systems and methods for non-invasive or minimally invasive collection and analysis of physiological data (e.g., blood pressure, electrolytes, genetic markers, B cell repertoire) to assess patient health status, screen for conditions, or aid in diagnosis.
Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.
Implantable devices designed to repair, replace, or assist the function of blood vessels or heart structures, including stents, valves, and annuloplasty rings.
Devices and methods utilizing ultrasound energy for non-invasive or minimally invasive treatment, including focused ultrasound for tissue ablation, neuromodulation, or enhanced substance delivery.
Self-contained or modular devices designed to automate and integrate multiple steps of molecular diagnostic assays, from sample preparation to result interpretation, often for point-of-care or high-throughput applications.
Systems and methods that use imaging technologies, computer vision, and augmented reality to provide real-time guidance, localization, and visualization during surgical procedures or for detailed anatomical assessment.
Focuses on the design of medical equipment for ease of use, mobility, and adaptability in various clinical or home environments, including carts, mounting systems, and compact form factors.
Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.
Utilizing machine learning, particularly deep learning, to analyze medical data such as images, sensor readings, or physiological signals for disease prediction, diagnosis, or treatment assessment.
Focuses on the mechanical design, articulation, and actuation of hand-held or robotic surgical instruments, including improvements in stapling, cutting, grasping, and tissue manipulation.
Implantable devices that deliver electrical, optical, or other forms of energy to stimulate tissues or nerves, or sense physiological parameters for therapeutic purposes.
Implantable devices designed to manage or redirect bodily fluids, including stents for ducts, and systems for draining or accumulating fluids within internal cavities.
Mechanical or electromechanical systems designed for precise, often self-administered, delivery of medicaments, including features for dose setting, needle insertion/retraction, and safety mechanisms to prevent premature activation.
Patents
Showing 1-10 of 240