Company patents

BioNTech SE

BioNTech SE's patent strategy shows a strong, albeit fluctuating, focus on core pharma_biotech areas, with Pharmaceutical Preparations (72.1% of portfolio), Peptides & Proteins (41.2%), and Therapeutic Activity (Pharma) (38.8%) dominating. While these categories saw significant growth in 2024 (e.g., Pharmaceutical Preparations +87.0%, Peptides & Proteins +107.7%), there's a notable decline in patenting activity across most categories in 2025 and so far in 2026, with Fermentation & Biosynthesis and Bioinformatics seeing a 100% decline in 2026, suggesting a potential shift in R&D priorities or a more selective patenting approach after a period of rapid expansion.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

165 US filings (since 2023) · 8 categories · 21 themes

Nucleic Acid-Based Therapies

Therapeutic strategies employing nucleic acids (DNA, RNA, oligonucleotides) to modulate gene expression, deliver genetic material, or interfere with disease-causing pathways. Includes gene therapy using viral vectors.

Pharmaceutical PreparationsTherapeutic Activity (Pharma)
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79since 2023
+19.2%YoY
Immunomodulatory Protein Design

Design and engineering of proteins or peptides to directly modulate immune responses, including enhancing antigen presentation, suppressing inflammation, or activating specific immune cell types.

Peptides & Proteins
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47since 2023
-27.8%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Peptides & ProteinsPharmaceutical PreparationsTherapeutic Activity (Pharma)Material & Chemical Analysis
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36since 2023
-42.9%YoY
Advanced Cell & Gene Therapies

Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.

Pharmaceutical PreparationsPeptides & Proteins
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34since 2023
+128.6%YoY
Advanced Drug Delivery Systems

Development of lipid-based nanoparticles, liposomes, or other molecular platforms to encapsulate and deliver therapeutic agents, particularly nucleic acids, to target tissues or improve pharmacokinetics.

Nanotechnology
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31since 2023
0.0%YoY
Immune Checkpoint Modulation

Therapeutic interventions that target immune checkpoint pathways to either enhance or suppress immune responses, often used in cancer immunotherapy or autoimmune diseases.

Therapeutic Activity (Pharma)
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27since 2023
-38.5%YoY
Targeted Drug Formulation Delivery

Delivery systems specifically engineered to administer advanced drug formulations (e.g., microparticles, biologics, extended-release systems) to achieve precise targeting, controlled release kinetics, or enhanced therapeutic efficacy within the body.

Pharmaceutical Preparations
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26since 2023
+10.0%YoY
Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
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22since 2023
-60.0%YoY
Clinical Diagnostics & Prognostics

Computational methods and systems for analyzing biological data (e.g., genomic, proteomic, clinical) to diagnose diseases, predict patient prognosis, assess treatment response, or stratify patients for therapy.

Bioinformatics
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16since 2023
-40.0%YoY
Recombinant Protein & Peptide Therapeutics

Development and application of therapeutic proteins or peptides produced through recombinant DNA technology, including fusion proteins and modified growth factors.

Therapeutic Activity (Pharma)
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15since 2023
+166.7%YoY
Cellular Immunotherapy

Therapeutic approaches involving the use of living cells, often genetically modified or ex vivo activated, to treat diseases, particularly cancer, by modulating immune responses or replacing damaged cells.

Therapeutic Activity (Pharma)
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14since 2023
-50.0%YoY
Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
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9since 2023
+150.0%YoY
Targeted Small Molecule Therapeutics

Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.

Pharmaceutical Preparations
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7since 2023
-75.0%YoY
CRISPR-based Nucleic Acid Detection

Assays leveraging CRISPR-Cas systems (e.g., Cas12, Cas13) for highly specific and sensitive detection of target nucleic acids, often involving collateral cleavage activity or reporter molecules.

Genetic & Microbiological Assays
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5since 2023
+50.0%YoY
Nucleic Acid Capture & Prep

Methods and reagents designed to improve the specificity, efficiency, or yield of nucleic acid capture, ligation, amplification, or library preparation steps, particularly for sequencing applications or quantitative analysis.

Genetic & Microbiological Assays
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5since 2023
+200.0%YoY
Bioprocess Optimization and Control

Developing advanced bioreactor designs, fermentation strategies, and downstream processing techniques to optimize yield, purity, and efficiency of biotechnological production.

Fermentation & Biosynthesis
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4since 2023
+100.0%YoY
Advanced Genomic Sequence Analysis

Computational techniques and algorithms for processing, aligning, and interpreting raw biological sequence data (DNA, RNA, protein), including identifying genetic variations, classifying organisms, or predicting sequence attributes.

Bioinformatics
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3since 2023
+100.0%YoY
Computational Biology & Drug Discovery Design

Applying computational methods, often involving machine learning and multiomics data, to design, analyze, and understand biomolecules, genetic sequences, or complex biological systems.

Bioinformatics
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3since 2023
+100.0%YoY
Molecular Biomarkers for Disease

Identification and measurement of specific nucleic acid sequences (DNA, RNA), their expression levels, or epigenetic modifications (e.g., methylation) as indicators for disease presence, progression, risk, or treatment response.

Genetic & Microbiological Assays
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3since 2023
0.0%YoY
Multi-omics Data Integration

Methods and systems for combining and analyzing diverse biological datasets (e.g., genomics, transcriptomics, proteomics, metabolomics) to uncover complex biological relationships, disease mechanisms, or temporal trajectories.

Bioinformatics
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1since 2023
new
Microbiome & Susceptibility Profiling

Techniques for identifying microorganisms, assessing their viability, quantifying their presence, profiling their metabolic activity, or determining their susceptibility to antimicrobial agents, often in complex biological or environmental samples.

Genetic & Microbiological Assays
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1since 2023
n/a

Patents

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