BOSTON SCIENTIFIC LIMITED

Embodiments herein relate to bioprosthetic heart valves. In an embodiment, a heart valve replacement system is included having a delivery catheter can include a heart valve accommodation region; and a heart valve disposed around the delivery catheter at the heart valve accommodation region of the delivery catheter, the heart valve can include a frame; and a plurality of valve leaflets coupled to the frame; wherein the valve leaflets include an animal tissue, the animal tissue can include from 15% to 50% by weight water; and from 20% to 70% by weight glycerol; a package defining an interior volume, wherein the delivery catheter and the heart valve are disposed within the package. Other embodiments are also included herein.

Embodiments include a valve leaflet for an implantable valve device comprising a leaflet body. The leaflet body comprising a free edge configured for coaptation with free edges of one or more other valve leaflets; and a root edge disposed opposite the free edge. The free edge defining an edge profile comprising a peak and valleys disposed on opposite sides of the peak. Other embodiments are also included herein.

A delivery catheter for a stent. The delivery catheter may have a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further includes a handle at its proximal end and at least one sheath which may at least partially circumferentially cover the stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on the handle portion. The catheter further includes at least one radio-opaque indicator for indicating a rotational orientation of the delivery catheter and/or the stent when observed using medical imaging during implantation of the stent.

A fluid management and medical device system may include a fluid management system and a medical device having one or more sensors proximate the distal end of the elongate shaft of the medical device. The controller of the fluid management system may be configured to calculate a fluid deficit when the distal end of the elongate shaft is disposed within a patient and configured to automatically pause fluid deficit calculation when the distal end of the elongate shaft is removed from the patient. In some instances the controller is configured to calculate the fluid deficit using rotational speed of the inflow pump in combination with a difference between a change in weight of a fluid supply source supplying fluid to the fluid management system and a change in weight of a collection container collecting fluid from the fluid management system.

A medical device that includes a clamp having a body defining a channel and a fixation member that is configured to move relative to the body from an unlocked position to a locked position. The medical device includes an actuator coupled to the fixation member and configured to move the fixation member from the unlocked position to the locked position. The fixation member extends at least partially into or radially outward from the channel in response to moving from the unlocked position to the locked position.

A delivery catheter for a stent. The delivery catheter may have a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further includes a handle at its proximal end and at least one sheath which may at least partially circumferentially cover the stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on the handle portion. The catheter further includes at least one radio-opaque indicator for indicating a rotational orientation of the delivery catheter and/or the stent when observed using medical imaging during implantation of the stent.

A direct stream hydrodynamic catheter system is provided for the removal of thrombus, lesions and the like including provisions for the infusion of drugs, lysing fluids and the like into a blood vessel. Physician controlled powered direct fluid jet streams emanate from a fluid jet emanatory in the form of robust radially directed fluid jet streams to impinge upon and ablate difficult and strong thrombus and lesions within a blood vessel. Effluent aspiration is controlled by an exhaust regulator in the form of a roller pump, but effluent removal can be assistingly influenced by the fluid pressure associated with the radially directed fluid jet streams.

A medical device, comprising: a handle, including: a handle body with a distal extension; a slot formed through the handle body, wherein the handle body includes a first sidewall and a second sidewall defining the slot; a first lumen disposed in the first sidewall, wherein the first lumen has an angled portion, and a portion of the first lumen runs parallel to the slot; and a second lumen extending between a distal end of the slot and the distal extension wherein the first lumen and the second lumen are interconnected at an intermediate point along a longitudinal length of the second lumen; a shaft extending distally from the handle; a first wire disposed within the first lumen, wherein the first wire connects the handle to the shaft; and a second wire disposed in the second lumen, wherein a portion of the second wire extends into the slot.

A medical device that includes a clamp having a body defining a channel and a fixation member that is configured to move relative to the body from an unlocked position to a locked position. The medical device includes an actuator coupled to the fixation member and configured to move the fixation member from the unlocked position to the locked position. The fixation member extends at least partially into or radially outward from the channel in response to moving from the unlocked position to the locked position.

The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to valve configurations providing sealable access for medical instruments to a working channel, such as a working channel for an endoscope.