Company patents

Codexis, Inc.

Codexis, Inc. demonstrates a strong and growing focus on Fermentation & Biosynthesis, which constitutes 56.4% of its total patent portfolio and experienced a significant 63.3% YoY growth in 2025, indicating a strategic deepening in this core area despite a partial decline so far in 2026. Conversely, the company appears to be shifting priorities away from Pharmaceutical Preparations, which saw an 83.3% decline in 2025 and no patents so far in 2026, and Therapeutic Activity (Pharma), which experienced a 100.0% decline in 2025.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

195 US filings (since 2023) · 6 categories · 11 themes

Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
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111since 2023
-11.6%YoY
Bioprocess Development for Proteins

Methods and systems for the efficient and scalable production, purification, and formulation of proteins and peptides, including fermentation, chromatography, and cell-based expression systems.

Peptides & Proteins
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75since 2023
+118.8%YoY
Enzyme Directed Evolution

Identifying novel enzymes or modifying existing enzymes through mutagenesis and directed evolution to improve catalytic activity, substrate specificity, or stability for industrial biotransformations.

Fermentation & Biosynthesis
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69since 2023
+12.5%YoY
Recombinant Protein & Peptide Therapeutics

Development and application of therapeutic proteins or peptides produced through recombinant DNA technology, including fusion proteins and modified growth factors.

Therapeutic Activity (Pharma)
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52since 2023
0.0%YoY
Recombinant Host Engineering

Modifying microorganisms, plant cells, or animal cells through genetic engineering to enhance or enable the biosynthesis of target compounds, often involving metabolic pathway engineering.

Fermentation & Biosynthesis
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28since 2023
+71.4%YoY
Targeted Small Molecule Therapeutics

Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.

Heterocyclic Compounds (Pharma)Pharmaceutical Preparations
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12since 2023
-40.0%YoY
Bioprocess Optimization and Control

Developing advanced bioreactor designs, fermentation strategies, and downstream processing techniques to optimize yield, purity, and efficiency of biotechnological production.

Fermentation & Biosynthesis
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11since 2023
0.0%YoY
Nucleic Acid Capture & Prep

Methods and reagents designed to improve the specificity, efficiency, or yield of nucleic acid capture, ligation, amplification, or library preparation steps, particularly for sequencing applications or quantitative analysis.

Genetic & Microbiological Assays
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8since 2023
-60.0%YoY
Chemical Synthesis of Drug Intermediates

Processes and methodologies for the efficient and scalable preparation of complex heterocyclic compounds and their precursors, including specific reaction conditions, purification techniques, and intermediate compounds.

Heterocyclic Compounds (Pharma)
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4since 2023
0.0%YoY
CRISPR-based Nucleic Acid Detection

Assays leveraging CRISPR-Cas systems (e.g., Cas12, Cas13) for highly specific and sensitive detection of target nucleic acids, often involving collateral cleavage activity or reporter molecules.

Genetic & Microbiological Assays
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3since 2023
+100.0%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Peptides & ProteinsTherapeutic Activity (Pharma)
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2since 2023
new

Patents

Showing 11-20 of 354

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