Company patents

Codexis, Inc.

Codexis, Inc. demonstrates a strong and growing focus on Fermentation & Biosynthesis, which constitutes 55.3% of its portfolio and saw a significant 63.3% growth in 2025, suggesting a core and expanding strategic area. Surprisingly, despite this growth, patenting activity in this category, along with Peptides & Proteins and Pharmaceutical Preparations, shows a sharp decline so far in 2026, with Fermentation & Biosynthesis down 85.7% and Pharmaceutical Preparations down 100.0% year-over-year, indicating a potential shift in immediate priorities or a cyclical patenting strategy.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

208 US filings (since 2023) · 5 categories · 9 themes

Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
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116since 2023
-11.6%YoY
Bioprocess Development for Proteins

Methods and systems for the efficient and scalable production, purification, and formulation of proteins and peptides, including fermentation, chromatography, and cell-based expression systems.

Peptides & Proteins
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80since 2023
+118.8%YoY
Enzyme Directed Evolution

Identifying novel enzymes or modifying existing enzymes through mutagenesis and directed evolution to improve catalytic activity, substrate specificity, or stability for industrial biotransformations.

Fermentation & Biosynthesis
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76since 2023
+12.5%YoY
Recombinant Protein & Peptide Therapeutics

Development and application of therapeutic proteins or peptides produced through recombinant DNA technology, including fusion proteins and modified growth factors.

Therapeutic Activity (Pharma)
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54since 2023
0.0%YoY
Recombinant Host Engineering

Modifying microorganisms, plant cells, or animal cells through genetic engineering to enhance or enable the biosynthesis of target compounds, often involving metabolic pathway engineering.

Fermentation & Biosynthesis
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30since 2023
+71.4%YoY
Targeted Small Molecule Therapeutics

Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.

Heterocyclic Compounds (Pharma)Pharmaceutical Preparations
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12since 2023
-40.0%YoY
Bioprocess Optimization and Control

Developing advanced bioreactor designs, fermentation strategies, and downstream processing techniques to optimize yield, purity, and efficiency of biotechnological production.

Fermentation & Biosynthesis
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11since 2023
0.0%YoY
Chemical Synthesis of Drug Intermediates

Processes and methodologies for the efficient and scalable preparation of complex heterocyclic compounds and their precursors, including specific reaction conditions, purification techniques, and intermediate compounds.

Heterocyclic Compounds (Pharma)
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4since 2023
0.0%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Peptides & ProteinsTherapeutic Activity (Pharma)
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2since 2023
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Patents

Showing 251-260 of 360

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