Company patents

Cytiva Sweden AB

Cytiva Sweden AB's patent strategy reveals a strong, consistent focus on 'Material & Chemical Analysis' (43.9% of portfolio) and 'Separation Processes (Filtration, Distillation)' (32.2%), both showing significant year-over-year fluctuations but rebounding in 2025 with +43.8% and +45.5% growth respectively. Surprisingly, despite its core biotech focus, the company shows an emerging interest in 'Industrial Control Systems' and 'Pumps (Positive Displacement)', both experiencing 100% and 200% growth in 2025, suggesting an increasing emphasis on the automation and physical infrastructure supporting its bioprocessing solutions.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

171 US filings (since 2023) · 12 categories · 27 themes

Automated Bioreactor Control

Systems and methods for automated monitoring and dynamic adjustment of environmental parameters (e.g., pH, temperature, oxygen, nutrients) and fluid handling within bioreactors to optimize cell/tissue growth or product synthesis.

Bioreactors / Cell Culture Apparatus
Who else files here? →
50since 2023
+53.8%YoY
Bioprocess Mixing Systems

Systems and components designed for mixing fluids in biological or pharmaceutical processes, often involving cell cultures, RNA synthesis, or nanoparticle formation, with considerations for sterility, automation, and precise control.

Mixing
Who else files here? →
42since 2023
-7.1%YoY
Bioprocess Development for Proteins

Methods and systems for the efficient and scalable production, purification, and formulation of proteins and peptides, including fermentation, chromatography, and cell-based expression systems.

Peptides & Proteins
Who else files here? →
31since 2023
-25.0%YoY
Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
Who else files here? →
25since 2023
+125.0%YoY
Bioreactor System Architecture

Innovations in the physical design and modularity of bioreactor vessels and associated components, focusing on improved handling, scalability, perfusion, or integration within larger systems.

Bioreactors / Cell Culture Apparatus
Who else files here? →
19since 2023
+75.0%YoY
Integrated Molecular Diagnostic Systems

Self-contained or modular devices designed to automate and integrate multiple steps of molecular diagnostic assays, from sample preparation to result interpretation, often for point-of-care or high-throughput applications.

Laboratory Apparatus
Who else files here? →
12since 2023
+33.3%YoY
Industrial & Bioprocess Filtration

Membrane and depth filtration for industrial separation, gas purification, and bioprocess clarification including cross-flow, dead-end, tangential flow filtration, and oil/water separation.

Separation Processes (Filtration, Distillation)Bioreactors / Cell Culture Apparatus
Who else files here? →
12since 2023
+200.0%YoY
Specialized Fluid Handling Connections

Couplings and fittings designed for specific fluid properties (e.g., cryogenic, chemical, medical, high-pressure) or requiring aseptic conditions, low-spill characteristics, or antimicrobial features to ensure safety and integrity.

Pipes & Tubing
Who else files here? →
11since 2023
+200.0%YoY
AM Process Monitoring & Control

Systems and methods for real-time sensing, modeling, and closed-loop control of additive manufacturing parameters to ensure part quality, consistency, and process efficiency. This includes thermal management, atmospheric regulation, and precise material deposition.

Industrial Control SystemsAdditive Manufacturing (3D Printing)
Who else files here? →
8since 2023
+50.0%YoY
Quick Connect/Disconnect Couplings

Mechanisms allowing rapid, secure, and often sealed attachment and detachment of pipes, tubes, or hoses, frequently featuring locking, sealing, and release components for efficient assembly and maintenance.

Pipes & Tubing
Who else files here? →
8since 2023
+200.0%YoY
Advanced Adsorbent & Separation Media

Development of materials with tailored porosity, surface chemistry, or structure, such as metal-organic frameworks (MOFs), zeolites, or superficially porous particles, for selective adsorption, ion exchange, or chromatographic separations.

Separation Processes (Filtration, Distillation)
Who else files here? →
7since 2023
0.0%YoY
Microfluidic Lab-on-Chip Devices

Miniaturized devices that manipulate small volumes of fluids (nanoliters to picoliters) through microchannels to perform laboratory functions like mixing, separation, reaction, and detection on a single chip.

Bioreactors / Cell Culture Apparatus
Who else files here? →
7since 2023
0.0%YoY
Portable and Compact Pump Devices

Design and engineering solutions for creating self-contained, mobile, or miniaturized pump systems, often incorporating battery power, ergonomic features, and integrated components for ease of use and transport.

Pumps (Positive Displacement)
Who else files here? →
6since 2023
+100.0%YoY
Bioreactor & Cell Culture Scaffolds

Devices and systems designed for the cultivation of cells or tissues, often incorporating three-dimensional structures or controlled interfaces to mimic in-vivo environments for biological research or production.

Laboratory Apparatus
Who else files here? →
5since 2023
+50.0%YoY
Industrial Solid-Liquid Separation

Equipment and processes for separating solid particles from liquid or gas phases in industrial settings, encompassing mechanical screening, filtration of molten materials, and various filter media designs.

Separation Processes (Filtration, Distillation)
Who else files here? →
5since 2023
-33.3%YoY
Pump Control and Efficiency

Techniques and systems for optimizing pump operation, including capacity modulation, energy management, pulsation reduction, and precise fluid dispensing to improve performance and reduce energy consumption.

Pumps (Positive Displacement)
Who else files here? →
5since 2023
+100.0%YoY
Gas Stream Purification

Technologies and systems for removing unwanted components or separating desired gases from a mixed gas stream, including adsorption, absorption, and membrane-based methods.

Separation Processes (Filtration, Distillation)
Who else files here? →
4since 2023
new
Integrated Actuation and Drive Systems

Methods and components for converting power into mechanical motion to drive pump mechanisms, encompassing electric motors, hydraulic actuators, and specialized motion converters like ball screws or solenoids.

Pumps (Positive Displacement)
Who else files here? →
3since 2023
new
Mixing System Thermal Control

Integration of heating, cooling, or temperature regulation mechanisms within mixing devices or vessels to maintain specific process temperatures, prevent overheating, or induce thermally-driven reactions.

Mixing
Who else files here? →
3since 2023
new
Advanced Cell & Gene Therapies

Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.

Peptides & Proteins
Who else files here? →
3since 2023
0.0%YoY
Cell Therapy & Bioproduction Processes

Methods and apparatus specifically tailored for the expansion, differentiation, or genetic modification of cells for therapeutic applications (e.g., CAR T cells, progenitor cells) or for the production of specific biological products (e.g., cultured fat, RNA).

Bioreactors / Cell Culture Apparatus
Who else files here? →
3since 2023
n/a
Advanced Sealing and Valve Design

Innovations in the design, materials, and maintenance of seals, valves, and related components to improve durability, reduce leakage, and enable specific pump functions like high-pressure operation or automated seal replacement.

Pumps (Positive Displacement)
Who else files here? →
2since 2023
0.0%YoY
Metal Additive Manufacturing Processes

Techniques for building three-dimensional metal objects layer-by-layer using metal powders, including powder bed fusion, binder jetting, and directed energy deposition. This theme encompasses process mechanics, equipment design, and operational control for AM systems.

Plastics Shaping & MoldingAdditive Manufacturing (3D Printing)
Who else files here? →
2since 2023
new
Inline & Continuous Mixing

Mixing apparatus designed for integration directly into a fluid conduit or a continuous process stream, often employing static elements, impellers within a flow path, or multi-component injection for efficient, uninterrupted processing.

Mixing
Who else files here? →
1since 2023
new
Smart Medication Management

Systems that integrate digital technology, sensors, or connectivity to monitor, track, or automate aspects of medication administration, often providing data feedback, personalized recommendations, or secure logging.

Healthcare Informatics
Who else files here? →
1since 2023
new
Multi-material Product Integration & Finishing

Techniques for combining multiple materials or layers, often with specialized surface treatments, coatings, or assembly methods, to create functional or aesthetically enhanced plastic articles, including consumer goods and encapsulated electronics.

Plastics Shaping & Molding
Who else files here? →
1since 2023
new
Water & Wastewater Membrane Treatment

Membrane-based separation for water purification, contaminant removal, desalination, and wastewater treatment, including reverse osmosis, ultrafiltration, and forward osmosis modules.

Separation Processes (Filtration, Distillation)
Who else files here? →
1since 2023
n/a

Patents

Showing 1-10 of 292

Page 1 of 30
US 12662655 B2GRANTED
C12M1/00

Device for distributing a flow

Filed:2019-12-10Pub:2026-06-23
Applicant:Cytiva Sweden AB

A flow distribution device for bioprocess systems, comprising: a flow distribution manifold ( 12; 112 ) comprising: at least four fluid connection conduits ( 14 ), wherein each fluid connection conduit ( 14 ) comprises a first end ( 18 ) for fluid connection and an opposite second end ( 20 ), and wherein at least three of the fluid connection conduits comprise a membrane ( 19 a ) and a valve seat ( 19 b ), which membrane ( 19 a ) can be put in at least two different positions in relation to the valve seat ( 19 b ) for allowing or preventing fluid flow between the first end ( 18 ) and the second end ( 20 ) of the fluid connection conduit ( 14 ); and a central common compartment ( 30 ) to which the second ends ( 20 ) of each of the fluid connection conduits ( 14 ) are connected, whereby the first ends ( 18 ) of each of the fluid connection conduits ( 14 ) can be in fluid communication with the central common compartment ( 30 ) and wherein the fluid connection conduits ( 14 ) are entering the central common compartment ( 30 ) from at least three different directions; wherein said flow distribution device ( 10 ) further comprises at least three membrane actuation members ( 41 ) which are provided in connection with one membrane ( 19 a ) of the flow distribution manifold ( 12; 112 ) each, wherein each of said membrane actuation members ( 41 ) is configured for actuating the membrane ( 19 a ) to be in at least two different positions in relation to the valve seat ( 19 b ), wherein a first position of the membrane ( 19 a ) allows flow between the first end ( 18 ) and the second end ( 20 ) of the fluid connection conduit ( 14 ) and a second position of the membrane ( 19 a ) prevents flow between the first end ( 18 ) and the second end ( 20 ) of the fluid connection conduit ( 14 ).

US 12655381 B2GRANTED
C12M1/36

Fluid coupling network for sampling a bioreactor

Filed:2021-10-13Pub:2026-06-16
Applicant:CYTIVA SWEDEN AB

The present invention relates to a computer implemented method for controlling a fluid coupling network ( 170 ), the fluid coupling network ( 170 ) being configured to be fluidly couplable to bioreactor ( 110 ), a gas source ( 120 ), a buffer source ( 140 ), a waste port ( 150 ), a processing system ( 160 ) and a conduit reservoir ( 208 ), the fluid coupling network ( 170 ) comprising a barrier unit ( 220 ) configured to sterilely separate fluid paths within the fluid coupling network ( 170 ), the fluid coupling network ( 170 ) being controllable to sample the bioreactor ( 110 ), the method comprising obtaining ( 510 ) a fluid sample from the bioreactor ( 110 ), wherein the step of obtaining the fluid sample comprises controlling a flow of fluid from the bioreactor ( 110 ) via the conduit reservoir ( 208 ) and the fluid coupling network ( 170 ) to the waste port ( 150 ), to fill the conduit reservoir ( 208 ) with the fluid from the bioreactor ( 110 ), providing ( 530 ) the fluid sample, wherein the step of providing the fluid sample comprises to provide the fluid sample to the processing system ( 160 ) from the conduit reservoir ( 208 ) via the fluid coupling network ( 170 ), and returning ( 540 ) residual fluid sample to the bioreactor ( 110 ), wherein the residual fluid sample is comprised by a part of the fluid coupling network ( 170 ) separated by the barrier unit ( 220 ), wherein the step of returning residual fluid sample comprises controlling a flow of gas from a gas source ( 120 ) to the bioreactor ( 110 ) via the part of the fluid coupling network ( 170 ).