Company patents

ETH ZURICH

ETH Zurich's patent strategy reveals a strong, albeit fluctuating, focus on pharmaceutical and materials science, with Pharmaceutical Preparations and Material & Chemical Analysis accounting for 15.2% and 17.5% of its portfolio, respectively. While categories like Therapeutic Activity (Pharma) saw a remarkable 500.0% YoY growth in 2024, many key areas, including Material & Chemical Analysis and Pharmaceutical Preparations, show significant declines in patenting activity so far in 2026 (down 60.0% and 50.0% respectively), suggesting a potential shift in research priorities or a natural ebb in patentable discoveries.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

171 US filings (since 2023) · 12 categories · 27 themes

Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
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20since 2023
-16.7%YoY
Advanced Cell & Gene Therapies

Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.

Peptides & ProteinsPharmaceutical Preparations
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9since 2023
+200.0%YoY
Targeted Small Molecule Therapeutics

Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.

Heterocyclic Compounds (Pharma)Pharmaceutical Preparations
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9since 2023
-33.3%YoY
Bioprocess Development for Proteins

Methods and systems for the efficient and scalable production, purification, and formulation of proteins and peptides, including fermentation, chromatography, and cell-based expression systems.

Peptides & Proteins
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8since 2023
+50.0%YoY
Biocompatible Scaffolds & Implants

Materials and structures designed for implantation or tissue regeneration, focusing on properties like biodegradability, mechanical strength, cellular integration, and long-term in-vivo stability.

Sterilization & Biocompatible Materials
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8since 2023
+50.0%YoY
In Vitro Disease Modeling & Cell Engineering

Development and use of engineered biological systems, such as organ-on-a-chip devices, dynamic hydrogels, or genetically modified cells, to mimic physiological conditions, study disease mechanisms, screen compounds, or develop cell-based therapies.

Material & Chemical Analysis
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7since 2023
-33.3%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Pharmaceutical PreparationsPeptides & ProteinsTherapeutic Activity (Pharma)Material & Chemical Analysis
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6since 2023
+50.0%YoY
Targeted Drug Formulation Delivery

Delivery systems specifically engineered to administer advanced drug formulations (e.g., microparticles, biologics, extended-release systems) to achieve precise targeting, controlled release kinetics, or enhanced therapeutic efficacy within the body.

Pharmaceutical Preparations
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5since 2023
0.0%YoY
Bioreactor & Cell Culture Scaffolds

Devices and systems designed for the cultivation of cells or tissues, often incorporating three-dimensional structures or controlled interfaces to mimic in-vivo environments for biological research or production.

Laboratory Apparatus
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5since 2023
+100.0%YoY
Targeted Protein Degradation

Development of small molecules, often bifunctional (e.g., PROTACs) or molecular glues, that induce the ubiquitin-proteasome system or autophagy to selectively degrade specific disease-causing proteins.

Heterocyclic Compounds (Pharma)
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5since 2023
-50.0%YoY
Cellular Immunotherapy

Therapeutic approaches involving the use of living cells, often genetically modified or ex vivo activated, to treat diseases, particularly cancer, by modulating immune responses or replacing damaged cells.

Therapeutic Activity (Pharma)
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4since 2023
+200.0%YoY
Chemical Synthesis of Drug Intermediates

Processes and methodologies for the efficient and scalable preparation of complex heterocyclic compounds and their precursors, including specific reaction conditions, purification techniques, and intermediate compounds.

Heterocyclic Compounds (Pharma)
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4since 2023
0.0%YoY
Interventional Device Materials & Design

Engineering and material considerations for devices used in minimally invasive procedures, focusing on mechanical properties, deployment mechanisms, and interaction with biological tissues.

Sterilization & Biocompatible Materials
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4since 2023
-66.7%YoY
Surgical Instrument Mechanisms

Focuses on the mechanical design, articulation, and actuation of hand-held or robotic surgical instruments, including improvements in stapling, cutting, grasping, and tissue manipulation.

Medical Diagnostics & Surgery
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3since 2023
+100.0%YoY
Microfluidic Lab-on-Chip Devices

Miniaturized devices that manipulate small volumes of fluids (nanoliters to picoliters) through microchannels to perform laboratory functions like mixing, separation, reaction, and detection on a single chip.

Laboratory Apparatus
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3since 2023
0.0%YoY
Advanced Adsorbent & Separation Media

Development of materials with tailored porosity, surface chemistry, or structure, such as metal-organic frameworks (MOFs), zeolites, or superficially porous particles, for selective adsorption, ion exchange, or chromatographic separations.

Catalysts & Reactors
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3since 2023
0.0%YoY
CRISPR-based Nucleic Acid Detection

Assays leveraging CRISPR-Cas systems (e.g., Cas12, Cas13) for highly specific and sensitive detection of target nucleic acids, often involving collateral cleavage activity or reporter molecules.

Genetic & Microbiological Assays
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3since 2023
new
Metal Additive Manufacturing Processes

Techniques for building three-dimensional metal objects layer-by-layer using metal powders, including powder bed fusion, binder jetting, and directed energy deposition. This theme encompasses process mechanics, equipment design, and operational control for AM systems.

Additive Manufacturing (3D Printing)
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3since 2023
new
Wearable Physiological Sensing

Development of devices and methods for non-invasive or minimally invasive collection and analysis of physiological data, often from wearable sensors, to monitor health, activity, or specific conditions.

Medical Diagnostics & Surgery
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2since 2023
+100.0%YoY
Microbiome & Susceptibility Profiling

Techniques for identifying microorganisms, assessing their viability, quantifying their presence, profiling their metabolic activity, or determining their susceptibility to antimicrobial agents, often in complex biological or environmental samples.

Genetic & Microbiological Assays
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2since 2023
new
Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
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2since 2023
new
Nucleic Acid Capture & Prep

Methods and reagents designed to improve the specificity, efficiency, or yield of nucleic acid capture, ligation, amplification, or library preparation steps, particularly for sequencing applications or quantitative analysis.

Genetic & Microbiological Assays
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2since 2023
n/a
AM Part Design & Topology Optimization

Computational methods and design principles for generating optimized geometries, internal structures (e.g., lattices, minimal surfaces), or functional features that are specifically enabled or enhanced by the capabilities of additive manufacturing.

Additive Manufacturing (3D Printing)
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1since 2023
new
Emerging Contaminant Removal

Specific techniques and materials developed to remove persistent or difficult-to-treat pollutants from water, such as per- and polyfluoroalkyl substances (PFAS), micropollutants, or specific industrial chemicals.

Catalysts & Reactors
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1since 2023
new
Carbon Dioxide Capture & Conversion

Technologies and materials for capturing carbon dioxide from gas streams and subsequently converting it into valuable chemical products or materials, rather than simply storing it.

Catalysts & Reactors
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1since 2023
n/a
Rapid Isothermal Amplification

Methods and kits for amplifying nucleic acids at a constant temperature, enabling faster results and point-of-care applications, often used for pathogen or contamination detection.

Genetic & Microbiological Assays
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1since 2023
n/a
Video Enhancement & Object Tracking

Methods and systems for improving the quality of video streams, generating intermediate frames, or continuously locating and following objects within a sequence of images, even under occlusion.

Image Processing
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1since 2023
n/a

Patents

Showing 1-10 of 276

Page 1 of 28
US 20260102387 A1APPLICATION
A61K31/4709

IMMUNOSUPPRESSIVE COMPOUNDS

Filed:2023-09-30Pub:2026-04-16
Applicant:UNIVERSITÄT BASEL

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, diastereoisomer, enantiomer, polymorph, racemic mixture, solvate or isomers and mixtures thereof. The invention further relates to a process for the stereoselective preparation of such compounds. The compound of formula (I) can be used as a medicament, in particular for inhibiting coronin 1 expression in the induction of immunosuppression or in the treatment and/or prevention of a disease or disorder selected from the group consisting of transplant rejection, autoimmune diseases, inflammatory diseases, infectious diseases, and lymphoproliferative disorders. The present invention further relates to a vector comprising a coronin 1 promoter element, wherein in a vertebrate genome, said coronin 1 promoter element starts directly upstream from a transcription starting site (TSS) of a coronin 1 gene and spans a sequence stretch of at least about 700 bp in said genome. The present invention further relates to a method using said vector for identifying immunomodulatory compounds that alter the coronin 1 promoter activity. The present invention further relates to BRD3 as an upstream target responsible for driving the coronin-1 expression and activity in immune cells, and relates to compounds, in particular compound of formula (I), that selectively target bromodomains of BRD3 and thereby deplete coronin 1 levels.