GAMBRO LUNDIA AB

The present disclosure sets forth a peritoneal dialysis (“PD”) system, which allows the lowest operating ambient temperature of the PD fluid to be decreased without modifying the heater power or the flow rate during treatment. The system includes a PD machine or cycler. Fresh PD fluid is delivered via a single or dual lumen patient line to the patient and is first heated to a body fluid temperature, e.g., 37° C. Before fill, the PD fluid is preheated by pumping the fresh PD fluid from a solution bag, through the inline heater, into an empty solution bag, and back until the fresh PD fluid is heated to a pre-determined temperature. This allows the initial temperature of the fresh PD fluid in the solution bag to be lower.

The present disclosure relates to a filtration device comprising a plurality of hollow fiber membranes. In particular, a filtration device comprising a plurality of microporous hollow fiber membranes having a large inner diameter and a thin wall is provided. The filtration device can be used for sterile dead-end filtration of liquids destined for infusion into a patient. Processes for production of the filtration device are also provided.

An apparatus for extracorporeal treatment of fluid and a process of setting up a medical apparatus for the delivery or collection of fluids are disclosed. According to the apparatus and the process, a control unit ( 10 ) is configured calculate set values of two or more of the fluid flow rates based on a fluid flow rate set by the operator and on a prescribed dose value (D set ).

Provide herein are a control arrangement and method for evaluating the integrity of a forward osmosis (FO-) membrane of a FO device in a dialysis solution generation apparatus. The FO-membrane separates a feed side and a draw side of the FO device. The FO-device comprises a feed inlet port and a feed outlet port in fluid communication with the feed side, and a draw inlet port and a draw outlet port in fluid communication with the draw side. The method comprises providing a flow of feed solution at the feed side via the feed inlet port and providing a flow of draw solution at the draw side via the draw inlet port, with an osmotic pressure at the draw side that is higher than an osmotic pressure at the feed side. Water is extracted from the feed side to the draw side to dilute the draw solution.

A control system operates ( 201 ) an apparatus for extracorporeal blood processing to extract, process and return the blood of an individual while removing fluid from the blood in accordance with a set value for ultrafiltration rate, UFR. The control system further obtains ( 202 ) sensor data representing one or more physiological parameters of the individual, and intermittently performs an optimization procedure ( 203 ) to generate the set value based on the sensor data. The optimization procedure comprises: evaluating ( 203 A) the sensor data for detection of a limiting physiological status, LPS, sequentially controlling ( 203 B) the apparatus in accordance with a test sequence of UFRs until the LPS is detected for a current UFR, and updating ( 203 C) the set value based on the current UFR for use in operating the apparatus subsequent to the optimization procedure. The control system may perform a series of temporally separated optimization procedures during a treatment session to adapt the UFR to the individual.

An extracorporeal blood treatment apparatus ( 1 ) has a filtration unit ( 2 ), a blood circuit ( 6 ), and a main infusion line ( 9 ) connected to a blood withdrawal line ( 6 a ) to infuse a solution into blood. A main infusion pump ( 11 ) causes the infusion solution I to flow from an infusion fluid source ( 10 ) to the blood withdrawal line, and an inactivated condition, wherein the main infusion pump ( 11 ) is inactive; a concentrate sensor ( 12 ) is placed on the blood withdrawal line between an injection point ( 9 a ) and the filtration unit ( 2 ) for monitoring the concentration of a substance. A control unit ( 13 ), in the first operating condition, activates the main infusion pump ( 11 ) and acquires the signal from the concentrate sensor ( 12 ) to determine the concentration of the substance into blood infused with the infusion solution, and, in the second operating condition, inactivates the main infusion pump ( 11 ) and acquires the signal to determine the concentration of the substance when no infusion solution I is infused into the blood.

A renal failure therapy system includes a fresh dialysis fluid tube having a connector for connecting to a dialyzer, a spent dialysis fluid tube having a connector for connecting to the dialyzer, a dialysis fluid circuit including a fresh dialysis fluid line, a spent dialysis fluid line, at least one of (i) a first disinfection device positioned between the fresh dialysis fluid line and the fresh dialysis fluid tube, or (ii) a second disinfection device positioned between the spent dialysis fluid line and the spent dialysis fluid tube, and recirculation circuitry extending to a first machine connector for mating with the connector of the fresh dialysis fluid tube during disinfection and a second machine connector for mating with the connector of the spent dialysis fluid tube during disinfection. The system also includes a control unit configured to cause the first and second disinfection devices to be energized during the local disinfection.

An optical detection apparatus is arranged to detect particles in a fluid flowing through a tubing portion of transparent or translucent material. The apparatus comprises a holder for the tubing portion; a light emitting device configured to irradiate a target volume inside the tubing portion when arranged in the holder; and at least one light receiving device configured to receive light from the target volume when irradiated by the light emitting device and generate one or more time-dependent output signals indicative of the received light. A computation device is configured to determine a parameter indicative of temporal variability in the one or more time-dependent output signals and estimate the density based on the parameter, which has been found to be robust to structural differences between tubings and allows the apparatus to be deployed without calibration.

The present disclosure relates to a process for testing the integrity of membranes in a filter module. Specifically, the process is applied to filters for extracorporeal blood treatment, in particular, filters comprising both filter membranes and particulate material.

An apparatus for extracorporeal blood treatment comprising a filtration unit, a blood circuit comprising a blood withdrawal line and a blood return line, and a fluid circuit. The fluid circuit comprises at least one or more water inlet ducts for receiving water, a dialysis preparation assembly comprising one or more concentrated sources housing a respective concentrate solution and configured to prepare a mixed solution of a dialysis fluid, wherein the water inlet duct is configured to provide water to the dialysis preparation assembly for preparing said mixed solution of dialysis fluid. The fluid circuit further comprises an infusion preparation assembly comprising one or more concentrated sources housing a respective concentrate solution and configured to prepare a mixed solution of an infusion fluid, wherein the water inlet duct is configured to provide water to the infusion preparation assembly for preparing said mixed solution of infusion fluid.