Company patents

Inovio Pharmaceuticals, Inc.

Inovio Pharmaceuticals, Inc. demonstrates a strong focus on core pharmaceutical innovation, with Pharmaceutical Preparations comprising 76.1% of its portfolio and Peptides & Proteins at 51.1%. While patenting in key areas like Therapeutic Activity (Pharma) saw a significant surge in 2024 with 18 patents (YoY +100.0%), the substantial year-over-year declines across most categories in 2025 and so far in 2026, such as Peptides & Proteins dropping by 47.6% in 2025 and 63.6% so far in 2026, suggest a potential shift in patenting strategy or a slowdown in new filings, despite a surprising emerging focus on Drug Delivery Devices, which saw a +100.0% growth so far in 2026 with 2 patents.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

92 US filings (since 2023) · 10 categories · 15 themes

Advanced Cell & Gene Therapies

Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.

Pharmaceutical PreparationsPeptides & Proteins
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30since 2023
+25.0%YoY
Nucleic Acid-Based Therapies

Therapeutic strategies employing nucleic acids (DNA, RNA, oligonucleotides) to modulate gene expression, deliver genetic material, or interfere with disease-causing pathways. Includes gene therapy using viral vectors.

Pharmaceutical PreparationsTherapeutic Activity (Pharma)
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22since 2023
-44.4%YoY
Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
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18since 2023
-50.0%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Peptides & ProteinsPharmaceutical PreparationsTherapeutic Activity (Pharma)Material & Chemical Analysis
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14since 2023
-77.8%YoY
Immunomodulatory Protein Design

Design and engineering of proteins or peptides to directly modulate immune responses, including enhancing antigen presentation, suppressing inflammation, or activating specific immune cell types.

Peptides & Proteins
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9since 2023
0.0%YoY
Cellular Immunotherapy

Therapeutic approaches involving the use of living cells, often genetically modified or ex vivo activated, to treat diseases, particularly cancer, by modulating immune responses or replacing damaged cells.

Therapeutic Activity (Pharma)
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9since 2023
+200.0%YoY
Automated Injector Mechanisms

Mechanical or electromechanical systems designed for precise, often self-administered, delivery of medicaments, including features for dose setting, needle insertion/retraction, and safety mechanisms to prevent premature activation.

Drug Delivery Devices
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7since 2023
+100.0%YoY
Immune Checkpoint Modulation

Therapeutic interventions that target immune checkpoint pathways to either enhance or suppress immune responses, often used in cancer immunotherapy or autoimmune diseases.

Therapeutic Activity (Pharma)
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5since 2023
+100.0%YoY
Closed-System Fluid Transfer

Devices and adapters that enable the sterile and secure transfer of liquids, such as medications or diluents, between containers (vials, syringes, IV bags) while minimizing exposure to contaminants or air.

Pharmacy Containers / Devices
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4since 2023
+100.0%YoY
Therapeutic Electromagnetic Fields

Use of alternating electric or magnetic fields at specific frequencies and intensities to achieve therapeutic effects, such as inhibiting cell proliferation (e.g., cancer) or modulating cytokine production.

Electrotherapy / Radiation Therapy
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3since 2023
n/a
Molecular Biomarkers for Disease

Identification and measurement of specific nucleic acid sequences (DNA, RNA), their expression levels, or epigenetic modifications (e.g., methylation) as indicators for disease presence, progression, risk, or treatment response.

Genetic & Microbiological Assays
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3since 2023
n/a
Recombinant Protein & Peptide Therapeutics

Development and application of therapeutic proteins or peptides produced through recombinant DNA technology, including fusion proteins and modified growth factors.

Therapeutic Activity (Pharma)
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2since 2023
0.0%YoY
Neuromodulation and Electrical Stimulation

Therapeutic application of electrical signals to nerves or tissues to modulate their activity, often using implantable devices, electrodes, and sophisticated programming for various conditions.

Electrotherapy / Radiation Therapy
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2since 2023
n/a
Targeted Drug Formulation Delivery

Delivery systems specifically engineered to administer advanced drug formulations (e.g., microparticles, biologics, extended-release systems) to achieve precise targeting, controlled release kinetics, or enhanced therapeutic efficacy within the body.

Drug Delivery Devices
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2since 2023
n/a
Automated Drug Dispensing

Devices or systems designed to precisely measure and deliver specific doses of medication, often incorporating automated mechanisms, dose-limiting features, or hands-free operation.

Pharmacy Containers / Devices
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2since 2023
n/a

Patents

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