INSTITUTE OF SCIENCE TOKYO

A phase modulation signal generating device for a fiber-optic gyroscope includes a sine wave generating part and a superimposing part. The sine wave generating part generates a fundamental sine wave of an odd-order frequency (v=(2n+1)v e , where n=0, 1, 2, . . . ) of the eigenfrequency (v e ) of the fiber-optic coil and a higher-order sine wave of an odd-order harmonic frequency ((2m+1) v, where m=1, 2, 3, . . . ) of the odd-order frequency (v). The superimposing part superimposes the fundamental sine wave and higher-order sine wave generated by the sine wave generating part at a ratio using a modulation index optimized according to a noise target to be minimized and outputs the resultant signal as a phase modulation signal.

A method of producing a protein crystal including adding, to a protein synthesis system, a nucleic acid that encodes crystalline protein; and incubating the protein synthesis system during the predetermined time until the crystalline protein encoded by the added nucleic acid is expressed and the expressed crystalline protein completes the formation of crystals. The protein synthesis system is a cell-free protein synthesis system.

An object of the present invention is to provide a lithium-based solid electrolyte having excellent ion conductivity, a method for producing a lithium-based solid electrolyte, a modified positive electrode active material, a modified negative electrode active material, an all-solid-state secondary battery, an electrode sheet for an all-solid-state secondary battery, a solid electrolyte sheet, and an electrode for an all-solid-state secondary battery. The lithium-based solid electrolyte of the present invention contains amorphous lithium tetraborate, water, and a lithium salt, in which a content of the water is 45% by mass or less with respect to a total mass of the lithium-based solid electrolyte.

A structural analysis apparatus includes: an acquisition unit that acquires measurement data which is a result of X-ray Diffraction (XRD) analysis of a crystal structure of an analysis target; a simulation unit that performs a simulation of XRD analysis on an estimation model of the crystal structure and generates simulation data corresponding to the measurement data; an evaluation unit that calculates an R value which is an index indicating a degree of matching between the measurement data and the simulation data, and calculates an energy value of the estimation model of the crystal structure; a model estimation unit that optimizes the estimation model of the crystal structure based on the R value and the energy value that are fed back from the evaluation unit and provides the optimized estimation model of the crystal structure to the simulation unit; and an output unit that outputs at least one estimation model.

The present invention provides a pharmaceutical composition for use in therapy or prevention of the novel coronavirus (SARS-CoV-2) disease 2019 (COVID-19), the composition containing an IL-10 inhibitor.

An anode structure according to an embodiment of the present disclosure is an anode structure applied to an anode of a lithium-ion secondary battery. The anode structure includes: an anode current collector, and a lithium alloy layer formed on the anode current collector. The lithium alloy layer has a stoichiometric composition represented by the formula Li 1-x-y Bi x Mg y (0<x+y≤0.124, 0≤x≤0.024, 0<y≤0.10), and the lithium alloy layer has a thickness of 1 μm or more and 20 μm or less.

A self-propelled elevator according to the present disclosure includes: a car; a first path which is used when the car moves in an up-down direction; a second path which is used when the car moves in a horizontal direction; a first rail which is provided along a longitudinal direction of the first path and along which the car slides; a second rail which is provided along the longitudinal direction of the first path and which guides movement of the car; a third rail which is provided along a longitudinal direction of the second path and along which the car slides; and a switching section which is provided at a position where the first and second paths intersect. The switching section includes a moving rail and a rotating section.

A solid electrolyte for a lithium secondary battery having a novel crystal structure and a method for producing the same is provided. The solid electrolyte has excellent lithium-ion conductivity and is chemically stable. The solid electrolyte comprises lithium (Li), germanium (Ge), and sulfur (S), forming a ternary compound with Ge 2 S 7 polyhedra and GeS 4 tetrahedra in a unit cell. The electrolyte may include compounds such as Li 16 Ge 5 S 18 and demonstrates lithium-ion conductivity of at least 8.7×10 −6 S·cm −1 at 25° C. Production methods involve either milling lithium and germanium sulfides to form an amorphous intermediate material, followed by heat treatment, or using crystalline raw materials like Li 2 GeS 3 and Li 4 GeS 4 directly. Both methods produce a stable, high-conductivity solid electrolyte suitable for all-solid-state lithium batteries, addressing safety and performance limitations of conventional electrolytes.

A tongue suction restrainer includes an upper fixing portion that is fixable to an upper jaw of a user when the tongue suction restrainer is attached to an oral cavity, an annular abutment portion that abuts on a hard palate of the user when the tongue suction restrainer is attached to the oral cavity, a recess formed at an inner side of the abutment portion to form a closed space with the hard palate in a state in which an entire circumference of the abutment portion abuts on the hard palate, a suction portion communicating with the recess to apply a negative pressure to the closed space, and a tongue suction portion formed at a position facing a tongue of the user when the tongue suction restrainer is attached to the oral cavity, has a suction hole provided to communicate with the recess, and that sucks the tongue by the negative pressure.

A production method for a crystal of a crystalline protein, the method including a step of inducing expression of a crystalline protein in Escherichia coli into which an expression construct of the crystalline protein has been introduced, and incubating the Escherichia coli for a predetermined time until a crystal of the crystalline protein is formed inside the Escherichia coli , and a crystal structure analysis method including a step of subjecting a crystal produced by the above-described production method to an X-ray crystal structure analysis together with the Escherichia coli , are useful as technologies for conveniently producing and analyzing a crystal of a protein.