Company patents

KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY

KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY's patent strategy reveals a strong, consistent focus on 'Pharmaceutical Preparations' (54.1% of portfolio) and 'Therapeutic Activity (Pharma)' (51.8% of portfolio), with both categories seeing significant growth in 2024 (77.8% and 125.0% YoY, respectively), although patenting in these areas has seen a decline in 2025 and so far in 2026. Surprisingly, while core pharma categories are dominant, the institute also shows an emerging interest in 'Heterocyclic Compounds (Pharma)', which saw a 50.0% YoY growth in 2026, indicating a potential shift towards specific chemical compound development within their broader pharmaceutical research.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

85 US filings (since 2023) · 12 categories · 29 themes

Advanced Cell & Gene Therapies

Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.

Pharmaceutical PreparationsPeptides & Proteins
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15since 2023
-75.0%YoY
Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
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13since 2023
-25.0%YoY
Targeted Small Molecule Therapeutics

Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.

Pharmaceutical PreparationsHeterocyclic Compounds (Pharma)
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11since 2023
0.0%YoY
Cellular Immunotherapy

Therapeutic approaches involving the use of living cells, often genetically modified or ex vivo activated, to treat diseases, particularly cancer, by modulating immune responses or replacing damaged cells.

Therapeutic Activity (Pharma)
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11since 2023
-50.0%YoY
Functional Foods & Supplements

Development of food compositions, beverages, or powders designed to provide specific health benefits beyond basic nutrition, such as weight management, anti-aging, exercise support, or targeted disease prevention/treatment, often incorporating bioactive compounds or probiotics.

Foods & Beverages
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10since 2023
0.0%YoY
Targeted Protein Degradation

Development of small molecules, often bifunctional (e.g., PROTACs) or molecular glues, that induce the ubiquitin-proteasome system or autophagy to selectively degrade specific disease-causing proteins.

Heterocyclic Compounds (Pharma)
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9since 2023
-83.3%YoY
Immunomodulatory Protein Design

Design and engineering of proteins or peptides to directly modulate immune responses, including enhancing antigen presentation, suppressing inflammation, or activating specific immune cell types.

Peptides & Proteins
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7since 2023
0.0%YoY
Novel Protein & Fermentation Technologies

Methods and compositions for developing new protein sources (e.g., microbial, plant-based blends) or utilizing controlled fermentation processes to create novel food products, improve nutritional profiles, or enhance specific characteristics like texture or flavor.

Foods & Beverages
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6since 2023
+200.0%YoY
In Vitro Disease Modeling & Cell Engineering

Development and use of engineered biological systems, such as organ-on-a-chip devices, dynamic hydrogels, or genetically modified cells, to mimic physiological conditions, study disease mechanisms, screen compounds, or develop cell-based therapies.

Material & Chemical Analysis
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6since 2023
-66.7%YoY
Plant Genetic Transformation

Methods and compositions for introducing, modifying, or expressing foreign genetic material within plant cells to confer new traits, produce novel compounds, or enhance existing characteristics.

New Plants / Plant Reproduction
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5since 2023
+100.0%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Therapeutic Activity (Pharma)Peptides & ProteinsPharmaceutical PreparationsMaterial & Chemical Analysis
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5since 2023
-33.3%YoY
Recombinant Protein & Peptide Therapeutics

Development and application of therapeutic proteins or peptides produced through recombinant DNA technology, including fusion proteins and modified growth factors.

Therapeutic Activity (Pharma)
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5since 2023
-33.3%YoY
Microbiome & Susceptibility Profiling

Techniques for identifying microorganisms, assessing their viability, quantifying their presence, profiling their metabolic activity, or determining their susceptibility to antimicrobial agents, often in complex biological or environmental samples.

Genetic & Microbiological Assays
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5since 2023
-50.0%YoY
Molecular Biomarkers for Disease

Identification and measurement of specific nucleic acid sequences (DNA, RNA), their expression levels, or epigenetic modifications (e.g., methylation) as indicators for disease presence, progression, risk, or treatment response.

Genetic & Microbiological Assays
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5since 2023
0.0%YoY
Targeted Drug Formulation Delivery

Delivery systems specifically engineered to administer advanced drug formulations (e.g., microparticles, biologics, extended-release systems) to achieve precise targeting, controlled release kinetics, or enhanced therapeutic efficacy within the body.

Pharmaceutical Preparations
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4since 2023
0.0%YoY
CRISPR-based Nucleic Acid Detection

Assays leveraging CRISPR-Cas systems (e.g., Cas12, Cas13) for highly specific and sensitive detection of target nucleic acids, often involving collateral cleavage activity or reporter molecules.

Genetic & Microbiological Assays
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4since 2023
0.0%YoY
Thermal Control for Bio-Reactions

Apparatus and methods for precisely controlling temperature profiles (heating, cooling, incubation) within laboratory reaction vessels or modules to optimize biochemical processes like gene amplification or protein assays.

Laboratory Apparatus
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4since 2023
new
Skin Anti-Aging & Repair Actives

Formulations and active ingredients designed to counteract signs of skin aging, such as wrinkles and hyperpigmentation, or to promote skin repair and regeneration through specific biological mechanisms.

Cosmetics & Personal Care Use
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4since 2023
-50.0%YoY
Nucleic Acid-Based Therapies

Therapeutic strategies employing nucleic acids (DNA, RNA, oligonucleotides) to modulate gene expression, deliver genetic material, or interfere with disease-causing pathways. Includes gene therapy using viral vectors.

Pharmaceutical PreparationsTherapeutic Activity (Pharma)
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3since 2023
0.0%YoY
New Crop & Ornamental Varieties

Development and characterization of novel plant varieties or cultivars, including field crops, vegetables, fruits, and ornamental plants, focusing on improved agronomic performance, aesthetic qualities, or specific product characteristics.

New Plants / Plant Reproduction
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3since 2023
+100.0%YoY
Nanostructured Sensors

Employs materials engineered at the nanoscale to create highly sensitive and selective sensors for detecting chemical, biological, or physical analytes, often leveraging plasmonic, photonic, or surface-enhanced Raman scattering (SERS) effects.

Nanotechnology
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3since 2023
0.0%YoY
Immune Checkpoint Modulation

Therapeutic interventions that target immune checkpoint pathways to either enhance or suppress immune responses, often used in cancer immunotherapy or autoimmune diseases.

Therapeutic Activity (Pharma)
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2since 2023
new
Bioprocess Development for Proteins

Methods and systems for the efficient and scalable production, purification, and formulation of proteins and peptides, including fermentation, chromatography, and cell-based expression systems.

Peptides & Proteins
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2since 2023
n/a
Nanostructured Membranes & Surfaces

Creation of membranes and surfaces with nanoscale features to control properties like porosity, hydrophobicity, or catalytic activity, particularly for applications in filtration, separation, and environmental remediation.

Nanotechnology
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1since 2023
new
Integrated Molecular Diagnostic Systems

Self-contained or modular devices designed to automate and integrate multiple steps of molecular diagnostic assays, from sample preparation to result interpretation, often for point-of-care or high-throughput applications.

Laboratory Apparatus
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1since 2023
new
Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
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1since 2023
n/a
Nucleic Acid Capture & Prep

Methods and reagents designed to improve the specificity, efficiency, or yield of nucleic acid capture, ligation, amplification, or library preparation steps, particularly for sequencing applications or quantitative analysis.

Genetic & Microbiological Assays
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1since 2023
n/a
Emulsion & Stabilizer Technologies

Innovations in creating stable cosmetic formulations, particularly oil-in-water or water-in-oil emulsions, and developing novel stabilizers or rheology modifiers for desired texture, feel, and shelf-life.

Cosmetics & Personal Care Use
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1since 2023
n/a
Nanomaterials for Optoelectronics

Involves the design and synthesis of semiconductor or perovskite nanocrystals and other nanostructures with tailored optical and electronic properties for advanced applications in light-emitting devices, displays, or quantum technologies.

Nanotechnology
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1since 2023
n/a

Patents

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