Company patents

Mammoth Biosciences, Inc.

Mammoth Biosciences, Inc. appears to be shifting its focus, with a surprising 700.0% year-over-year growth in Pharmaceutical Preparations patents in 2024, now representing 27.8% of its portfolio, while its core Genetic & Microbiological Assays category, though still dominant at 44.4%, has seen a significant decline in filings in 2025 and so far in 2026.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

54 US filings (since 2023) · 6 categories · 11 themes

CRISPR-based Nucleic Acid Detection

Assays leveraging CRISPR-Cas systems (e.g., Cas12, Cas13) for highly specific and sensitive detection of target nucleic acids, often involving collateral cleavage activity or reporter molecules.

Genetic & Microbiological Assays
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49since 2023
-64.0%YoY
Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
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31since 2023
-70.6%YoY
Nucleic Acid-Based Therapies

Therapeutic strategies employing nucleic acids (DNA, RNA, oligonucleotides) to modulate gene expression, deliver genetic material, or interfere with disease-causing pathways. Includes gene therapy using viral vectors.

Pharmaceutical PreparationsTherapeutic Activity (Pharma)
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23since 2023
-50.0%YoY
Nucleic Acid Capture & Prep

Methods and reagents designed to improve the specificity, efficiency, or yield of nucleic acid capture, ligation, amplification, or library preparation steps, particularly for sequencing applications or quantitative analysis.

Genetic & Microbiological Assays
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17since 2023
-70.0%YoY
Advanced Cell & Gene Therapies

Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.

Peptides & ProteinsPharmaceutical Preparations
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8since 2023
-50.0%YoY
Integrated Molecular Diagnostic Systems

Self-contained or modular devices designed to automate and integrate multiple steps of molecular diagnostic assays, from sample preparation to result interpretation, often for point-of-care or high-throughput applications.

Genetic & Microbiological AssaysLaboratory Apparatus
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4since 2023
n/a
Rapid Isothermal Amplification

Methods and kits for amplifying nucleic acids at a constant temperature, enabling faster results and point-of-care applications, often used for pathogen or contamination detection.

Genetic & Microbiological Assays
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2since 2023
n/a
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Pharmaceutical Preparations
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1since 2023
new
Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
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1since 2023
new
Molecular Biomarkers for Disease

Identification and measurement of specific nucleic acid sequences (DNA, RNA), their expression levels, or epigenetic modifications (e.g., methylation) as indicators for disease presence, progression, risk, or treatment response.

Genetic & Microbiological Assays
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1since 2023
n/a
Bioprocess Development for Proteins

Methods and systems for the efficient and scalable production, purification, and formulation of proteins and peptides, including fermentation, chromatography, and cell-based expression systems.

Peptides & Proteins
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1since 2023
n/a

Patents

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