MEDTRONIC MINIMED, INC.

A system for monitoring a patient includes one or more processors and a sensor device implemented in circuitry. The system is configured to measure, using the sensor device, a blood glucose status of the patient, and determine, using one or more processors, an initial insulin dose for the patient based on the blood glucose status of the patient. The system is further configured to optimize the initial insulin dose for the patient, based at least in part on a correction factor, to create an optimized insulin dose for the patient. The system is configured to facilitate therapy, using the one or more processors, based on the determined optimized insulin dose.

Analyte sensors and associated insertion devices are disclosed herein. According to some embodiments, the present technology includes a sensor applicator comprising a housing having an insertion end configured to be positioned at or adjacent a user's skin at an insertion site, a needle carried by the housing and configured for insertion into the user's skin at the insertion site, and a sensor assembly comprising a base and a sensing portion extending from the base. The base is supported by the housing in a first position during insertion of the needle and configured to rotate into a second, laid-flat position on the user's skin after removal of the housing from the insertion site.

Technologies are provided for insulin delivery. According to some aspects, a system may receive therapy-related data and settings associated with a first insulin infusion device used to deliver insulin to a user during a time period. The system may detect events during the period, via an event detection system, wherein each detected event comprises a specific activity that is indicative of a physical behavior of the user. The system may process the therapy-related data and settings to identify one or more physiological periods of the user, occurring during the time period, based on the detected events and the therapy-related data and settings, and may determine a physiological blood response of the user during the identified one or more physiological periods of the user. The system may output insulin delivery information for delivering insulin to the user based at least in part on the determined physiological blood response.

A hub member for an infusion set device includes a body and pads configured to receive a squeezing force directed radially inward relative to an axis of the body. The body compresses radially inward relative to the axis in response to the squeezing force. A plurality of connection features on the body are moveable from a first position radially inward toward a second position when the hub member is compressed radially inward. The plurality of connection features engage one or more further connection features on a housing to attach the hub member to the housing when the plurality of connection features are in the first position, and disengage the one or more further connection features to release the hub member when the plurality of connection features are moved toward the second position.

A medical device includes a base having a needle channel and a first surface configured to be secured to a patient's skin, the first surface attached to the patient's skin by an adhesive material layer attached to the first surface, one or more sensors located in the base, an insertable member including a first portion and a second portion contiguous with the first portion, the first portion coupled to the one or more sensors and the second portion extending through the needle channel and the first surface for insertion through the patient's skin at an insertion site, a septum extending across the needle channel and perpendicular to the second portion, the septum providing a liquid seal across the needle channel, where the needle channel and the septum provide a sealed volume in which a limited amount of blood or other fluid from the insertion site may be held.

An apparatus adherable to a user's skin, such as a wearable medical device, is presented here. An embodiment of the apparatus includes a durable component including a housing having a periphery and a skin adhesive component coupled to the durable component. The skin adhesive component adapted to secure the durable component to the user's skin. The apparatus further includes an overlay adhesive component to cover a portion of the skin adhesive component when adhered to the user's skin. The overlay adhesive component includes a protective adhesive region shaped and sized for compatibility with the portion of the skin adhesive component, and a central opening that accommodates passage of the housing of the durable component during deployment of the overlay adhesive component.

Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes as well as methods for making and using such sensors. The amperometric analyte sensor apparatus comprises: a base layer; a conductive layer disposed on the base layer and comprising a working electrode; an interference rejection membrane disposed on an electroactive surface of the working electrode, wherein the interference rejection membrane comprises poly(vinyl alcohol) (PVA) polymers crosslinked by an acid crosslinker, wherein the crosslinker is a dicarboxylic acid type monomer or a polymer comprising a carboxylic acid group; and an analyte sensing layer. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.

Disclosed is a medical device component for delivering infusion fluid to a patient. The medical device component includes a fluid infusion device to regulate delivery of medication fluid, a base, and a top cover assembly that is removably couplable to the base and to the fluid infusion device. The base includes a cannula to deliver medication fluid under the control of the fluid infusion device, and a physiological analyte sensor to measure a physiological characteristic. The base also includes an electronics assembly electrically connected to sensor leads to obtain measurements in the analog domain, to convert measurements into digital sensor data, and to communicate conditioned digital sensor data to the fluid infusion device. The top cover assembly is configured to provide both fluid and electrical connections for the base, by way of an infusion tube having sensor conductors integrated therein or otherwise associated therewith.

Techniques disclosed herein relate to calibrating glucose values. In some embodiments, the techniques may involve measuring one or more calibration values of an operating parameter of one or more monitor electrodes. The techniques may further involve determining one or more delta values using the one or more calibration values and one or more pre-calibration values, wherein the one or more delta values are indicative of a first reaction of a first chemistry stack of the one or more monitor electrodes. The techniques may further involve utilizing a relationship between a second reaction of a second chemistry stack disposed on one or more working electrodes and a first reaction of the first chemistry stack to translate the one or more delta values associated with the operating parameter of the one or more monitor electrodes to a change in an operating parameter of one or more working electrodes.

Disclosed herein are techniques related to sensor data calibration based on weighted values. In some embodiments, the techniques involve obtaining a plurality of sample values of an electrical signal generated by a sensor. Each sample value may be indicative of a concentration of an analyte in a first type of bodily fluid. Additionally, the techniques may involve obtaining a plurality of reference measurement values (RMVs). Each RMV may correspond to a concentration of the analyte in a second type of bodily fluid. The techniques may also involve temporally associating a first sample value to a first RMV and a second sample value to a second RMV, which is greater than the first RMV. The techniques may further involve applying a first weighting to the first sample value and a second weighting to the second sample value. The first weighting may be greater than the second weighting.