Mexichem Fluor S.A. de C.V.

A pharmaceutical composition comprises a drug component. The drug component is a combination of one pharmaceutically acceptable salt of glycopyrrolate, beclomethasone dipropionate, and one long acting beta-2-agonist (LABA) selected from formoterol and pharmaceutically acceptable salts thereof. The pharmaceutical composition also comprises a propellant component. The propellant component is at least 90 weight percent 1,1-difluoroethane (HFA-152a). The pharmaceutical composition is in the form of a solution and optionally comprises ethanol, but is free of other polar solvents/co-solvents. The drug component is the sole drug component in the pharmaceutical composition.

The use as a refrigerant of a composition comprising 1,1-difiuoroethyiene in a liquid chiller system.

A composition comprising trifluoroiodomethane (CF 3 I) and 1,1-difluoroethylene (R-1132a) is described. The composition can also comprise additional compounds, such as at least one non-flammable compound selected from the group consisting of carbon dioxide (CO2; R-744), tetrafluoromethane (R-14), trifluoromethane (R-23) and perfluoroethane (R-116) or at least one additional compound of lower volatility than 1,1-difluoroethylene selected from the group consisting of 1,1,2-trifluoroethylene (R-1123), difluoromethane (R-32), propane (R-290), propylene (R-1270), fluoroethane (R-161), pentafluoroethane (R-125), 1,1,1,2-tetrafluoroethane (R-134a), 2,3,3,3-tetrafluopropene (R-1234yf), isobutane (R-600a), n-butane (R-600), trans-1,3,3,3-tetrafluopropene (R-1234ze(E)), 3,3,3-trifluoropropene (R-1243zf), 1,2,3,3,3-pentafluoropropene (R-1225ye), 1, 1,1,2,3,3,3-heptafluoropropane (R-227ea), 1,1-difluoroethane (R-152a), cis-1,3,3,3-tetrafluopropene (R-1234ze(Z)), 1-chloro-3,3,3-trifluoropropene (R-1233zd(E/Z)) and 1,1,1,4,4,4-hexafluoro-2-butene (R-1336mzz(E/Z)). The compositions have utility as refrigerants in vapour compression heat transfer systems.

According to the present invention, there is provided a composition carbon dioxide (CO 2 , R-744), difluoromethane (R-32) and 1,1-difluoroethylene (R-1132 a ).

The invention provides a composition comprising carbon dioxide (CO2, R-744), difluoromethane (R-32) and trifluoroiodomethane (CF 3 I) and the use of such a composition as a working fluid in a heat transfer system, such as a refrigeration, heat pump or air-conditioning system.

A composition comprising: (i) 1,1-difluoroethene (vinylidene fluoride, R-1132a); (ii) carbon dioxide (CO 2 , R-744); (iii) pentafluoroethane (R-125); and (iv) one or more of trifluoromethane (R-23) and hexafluoroethane (R-116).

A method for activating a catalyst comprises the steps of: optionally drying the catalyst at a temperature of from 100° C. to 400° C.; treating the catalyst with a composition comprising HF at a temperature of from 500° C. to about 700° C.; and optionally treating the catalyst with a composition comprising an oxidant and optionally HF at a temperature of from about 100° C. to about 500° C.

Use as a refrigerant in a heat pump system in an electric vehicle of a composition is described. The composition comprises 1,1-difluoroethylene (R-1132a) and at least one fluorocarbon refrigerant compound selected from the group consisting of 2,3,3,3-tetrafluoropropene (R-1234yf), difluoromethane (R-32), 1,3,3,3-tetrafluoropropene (R-1234ze(E)) and 1,1-difluoroethane (R-152a).

A method for activating a catalyst comprises the steps of: a) optionally drying the catalyst at a temperature of from 100° C. to 400° C.; b) treating the catalyst with a composition comprising HF at a temperature of from 0° C. to about 500° C.; c) treating the catalyst with a composition comprising an oxidant and optionally HF at a temperature of from about 100° C. to about 500° C.

A method for at least partially draining an operating system, which contains a working fluid including carbon dioxide (R744) and a halogenated hydrocarbon. The method includes transferring the working fluid to a target container, from the operating system, wherein the working fluid is contacted with an absorptive bed. The working fluid may include between 10% and 35% by weight of halogenated hydrocarbon. The method may include an absorptive bed treatment step prior to the contacting step.