MOR RESEARCH APPLICATIONS LTD.

There is provided a method of diagnosing a medical state associated with a neuro-psychiatric disorder in a subject, comprising: receiving EEG datasets from EEG electrodes monitoring a head of the subject, computing events for the EEG datasets, clustering the events into clusters, computing a p-adic representation of the clusters, extracting a p-adic topology from the p-adic representation of the clusters, computing a personal universal dendrogramic holographic signature (PUDHS) of the p-acid topology relative to a personalized threshold that separates between a relative large distance between events and a relatively small distance between events, the PUDHS denoting number of events below the personalized threshold, and diagnosing the medical state associated with the neuro-psychiatric disorder according to the PUDHS relative to a medical threshold that separates between presence of the medical state and non-presence of the medical state.

Embodiments pertain to an ophthalmic tool for ab-interno removal of ophthalmic tissue from a human eye, the human eye including trabecular meshwork tissue and a Schlemm's canal. The tool comprises an excise device having a longitudinal centerline, and shaped and dimensioned pull-string for snug insertion into the Schlemm's canal, and has a leading nose, and a trailing knife support with a pair of spaced apart longitudinally directed knife blades mounted upright on the knife support.

The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human Triggering Receptor Expressed on Myeloid Cells 2 (TREM2). The anti-TREM2 antibodies or antigen-binding fragments thereof are useful, for example, in detecting TREM2 and in treating neurodegenerative diseases.

There is provided a computer implemented method of diagnosing a medical state associated with a neuro-psychiatric disorder in a subject, comprising: receiving a plurality of EEG datasets, each respective EEG dataset from a respective EEG electrode of a plurality of EEG electrodes monitoring a head of the subject, clustering the plurality of EEG datasets into a plurality of clusters, computing a p-adic representation of the plurality of clusters, extracting a quantum potential value from p-adic representation of the plurality of clusters, and diagnosing the medical state associated with the neuro-psychiatric disorder according to the quantum potential relative to a threshold that separates between presence of the medical state and non-presence of the medical state.

Methods for treatment of cornea epithelium pathologies and conditions, which may benefit from treatment of mitochondrial dysfunction, mitochondrial destruction and/or mitochondrial depletion in the eye, are disclosed. These methods comprise the transplantation of viable exogenous, isolated mitochondria to the cornea, for example, by topical application of designated eyedrops.

Embodiments pertain to a non-wearable monitoring system for monitoring activity of a human in a scene including a floor. The system may comprise a plurality of remote ranging emitters which are configured to emit ranging energy towards the scene. At least one first and at least one second emitter of the plurality of emitters are arranged to cover different height sections of the scene. The plurality of remote ranging emitters is arranged to obtain, based on the emitted ranging energy, reflections. The system further comprises a plurality of sensors which are configured to receive the reflections and to convert the reflections into electronic signals to generate reflection-based data. The system is configured to determine based on the reflection-based data, a posture and/or activity of the human in the scene.

Embodiments pertain to a cranial cap, adapted for covering, at least partially or fully, a skin flap of a patient's head having undergone a craniectomy, the cranial cap comprising: a cap body; a flexible sheet adaptable to adhere to the head; wherein the cap body and the flexible sheet are sealed to form a fluid-tight cavity; a tubing connector port for removably bringing a pump in fluid communication with the cavity such to enable controlling fluid pressure in the cavity; and at least one sensor adapted and disposed to sense at least one characteristic relating to a skin flap shape for responsively providing an output descriptive of or relating to the skin flap shape; and patient posture and/or patient movement.

Methods for treatment of ocular diseases and conditions associated with mitochondrial dysfunction, mitochondrial destruction and/or mitochondrial depletion in the eye, are disclosed. These methods comprise the transplantation of viable exogenous, isolated mitochondria to ocular tissues. Mitochondrial transplantation is effective in treatment of, e.g., an ocular manifestation of a disease or disorder in a subject, an ophthalmic disease, disorder or condition associated with mitochondrial dysfunction, and/or an ocular ischemic insult in a subject.

Embodiments pertain to a non-wearable monitoring system for monitoring activity of a human in a scene including a floor. The system may comprise a plurality of remote ranging emitters which are configured to emit ranging energy towards the scene. At least one first and at least one second emitter of the plurality of emitters are arranged to cover different height sections of the scene. The plurality of remote ranging emitters is arranged to obtain, based on the emitted ranging energy, reflections. The system further comprises a plurality of sensors which are configured to receive the reflections and to convert the reflections into electronic signals to generate reflection-based data. The system is configured to determine based on the reflection-based data, a posture and/or activity of the human in the scene.

The present disclosure relates to a device for treating obstructed airways. Specifically, the present disclosure relates to a device for treating the symptoms of diseases that cause persistent airflow limitation by applying air pressure oscillations and acoustic vibrations to the airways of a patient during treatment. The device may be used in a system that allows in-home treatment under remote supervision of a physician.