Company patents

Nautilus Subsidiary, Inc.

Nautilus Subsidiary, Inc. exhibits a strong focus on Material & Chemical Analysis, representing 63.4% of its portfolio, which saw an explosive 850.0% YoY growth in 2024, although it has since shown a -19.0% decline so far in 2026. Surprisingly, despite a significant presence in Genetic & Microbiological Assays (40.9% of portfolio), the company appears to be shifting priorities with a -25.0% decline in patenting in this area so far in 2026, alongside a notable -40.0% decline in Nanotechnology patenting for the same period.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

93 US filings (since 2023) · 12 categories · 15 themes

Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
Who else files here? →
85since 2023
-6.9%YoY
Nucleic Acid Capture & Prep

Methods and reagents designed to improve the specificity, efficiency, or yield of nucleic acid capture, ligation, amplification, or library preparation steps, particularly for sequencing applications or quantitative analysis.

Genetic & Microbiological Assays
Who else files here? →
45since 2023
-38.9%YoY
Bioprocess Development for Proteins

Methods and systems for the efficient and scalable production, purification, and formulation of proteins and peptides, including fermentation, chromatography, and cell-based expression systems.

Peptides & Proteins
Who else files here? →
33since 2023
+10.0%YoY
Integrated Molecular Diagnostic Systems

Self-contained or modular devices designed to automate and integrate multiple steps of molecular diagnostic assays, from sample preparation to result interpretation, often for point-of-care or high-throughput applications.

Genetic & Microbiological Assays
Who else files here? →
21since 2023
0.0%YoY
CRISPR-based Nucleic Acid Detection

Assays leveraging CRISPR-Cas systems (e.g., Cas12, Cas13) for highly specific and sensitive detection of target nucleic acids, often involving collateral cleavage activity or reporter molecules.

Genetic & Microbiological Assays
Who else files here? →
14since 2023
+25.0%YoY
Molecular Biomarkers for Disease

Identification and measurement of specific nucleic acid sequences (DNA, RNA), their expression levels, or epigenetic modifications (e.g., methylation) as indicators for disease presence, progression, risk, or treatment response.

Genetic & Microbiological Assays
Who else files here? →
11since 2023
-60.0%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Material & Chemical AnalysisPeptides & Proteins
Who else files here? →
8since 2023
-80.0%YoY
Computational Biology & Drug Discovery Design

Applying computational methods, often involving machine learning and multiomics data, to design, analyze, and understand biomolecules, genetic sequences, or complex biological systems.

Bioinformatics
Who else files here? →
7since 2023
0.0%YoY
Advanced Genomic Sequence Analysisfiltered

Computational techniques and algorithms for processing, aligning, and interpreting raw biological sequence data (DNA, RNA, protein), including identifying genetic variations, classifying organisms, or predicting sequence attributes.

Bioinformatics
Who else files here? →
7since 2023
new
Microfluidic Lab-on-Chip Devices

Miniaturized devices that manipulate small volumes of fluids (nanoliters to picoliters) through microchannels to perform laboratory functions like mixing, separation, reaction, and detection on a single chip.

Laboratory Apparatus
Who else files here? →
5since 2023
+50.0%YoY
Advanced Drug Delivery Systems

Development of lipid-based nanoparticles, liposomes, or other molecular platforms to encapsulate and deliver therapeutic agents, particularly nucleic acids, to target tissues or improve pharmacokinetics.

Nanotechnology
Who else files here? →
2since 2023
0.0%YoY
Automated Liquid Handling

Systems and components designed for precise, automated manipulation, transfer, and dispensing of liquid samples and reagents, often involving pipettes, robotic arms, and specialized sample containers.

Laboratory Apparatus
Who else files here? →
2since 2023
0.0%YoY
Nanostructured Membranes & Surfaces

Creation of membranes and surfaces with nanoscale features to control properties like porosity, hydrophobicity, or catalytic activity, particularly for applications in filtration, separation, and environmental remediation.

Nanotechnology
Who else files here? →
1since 2023
new
Immunomodulatory Protein Design

Design and engineering of proteins or peptides to directly modulate immune responses, including enhancing antigen presentation, suppressing inflammation, or activating specific immune cell types.

Peptides & Proteins
Who else files here? →
1since 2023
n/a
Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
Who else files here? →
1since 2023
n/a

Patents

Page 1 of 1