Company patents

Osaka University

Osaka University's patent strategy reveals a surprising shift away from its historically strong pharmaceutical focus, with 'Pharmaceutical Preparations' (21.2% of portfolio) seeing a significant decline of -57.1% so far in 2026, and 'Therapeutic Activity (Pharma)' (14.2% of portfolio) also down by -52.6% in the current partial year. While 'Welding & Soldering' experienced a remarkable 150.0% YoY growth in 2024, indicating a brief emerging focus, the overall trend across most categories, including 'Material & Chemical Analysis' and 'Medical Diagnostics & Surgery', shows a substantial decline in patenting activity so far in 2026, suggesting a broad re-evaluation or slowdown in new filings.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

628 US filings (since 2023) · 12 categories · 37 themes

Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
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66since 2023
-50.0%YoY
Advanced Cell & Gene Therapies

Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.

Pharmaceutical PreparationsPeptides & Proteins
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45since 2023
+21.4%YoY
Targeted Small Molecule Therapeutics

Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.

Pharmaceutical PreparationsHeterocyclic Compounds (Pharma)
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35since 2023
-36.4%YoY
Targeted Protein Degradation

Development of small molecules, often bifunctional (e.g., PROTACs) or molecular glues, that induce the ubiquitin-proteasome system or autophagy to selectively degrade specific disease-causing proteins.

Heterocyclic Compounds (Pharma)
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31since 2023
0.0%YoY
Nucleic Acid-Based Therapies

Therapeutic strategies employing nucleic acids (DNA, RNA, oligonucleotides) to modulate gene expression, deliver genetic material, or interfere with disease-causing pathways. Includes gene therapy using viral vectors.

Therapeutic Activity (Pharma)Pharmaceutical Preparations
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26since 2023
+28.6%YoY
In Vitro Disease Modeling & Cell Engineering

Development and use of engineered biological systems, such as organ-on-a-chip devices, dynamic hydrogels, or genetically modified cells, to mimic physiological conditions, study disease mechanisms, screen compounds, or develop cell-based therapies.

Material & Chemical Analysis
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22since 2023
-11.1%YoY
Immunomodulatory Protein Design

Design and engineering of proteins or peptides to directly modulate immune responses, including enhancing antigen presentation, suppressing inflammation, or activating specific immune cell types.

Peptides & Proteins
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20since 2023
+133.3%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Peptides & ProteinsPharmaceutical PreparationsTherapeutic Activity (Pharma)Material & Chemical Analysis
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18since 2023
+33.3%YoY
Welding & Soldering Tool Design

Design and features of welding and soldering tools, fixtures, and accessories that enhance user safety, ergonomics, operational efficiency, and precise workpiece manipulation, including protective equipment and clamping mechanisms.

Welding & Soldering
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17since 2023
-28.6%YoY
Cellular Immunotherapy

Therapeutic approaches involving the use of living cells, often genetically modified or ex vivo activated, to treat diseases, particularly cancer, by modulating immune responses or replacing damaged cells.

Therapeutic Activity (Pharma)
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16since 2023
+20.0%YoY
Welding Process Control

Systems and methods for precisely controlling welding parameters such as power, speed, oscillation, and material feed to optimize weld quality, consistency, and efficiency, often involving automated or semi-automated processes.

Welding & Soldering
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16since 2023
-33.3%YoY
Liquid Crystal Compositions

Mixtures of liquid crystal compounds and other additives, such as monomers or carbon black, designed to achieve specific optical, electrical, or physical properties for use in liquid crystal displays (LCDs) or other electro-optical devices.

Functional Materials (LCD, Lubricants)
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14since 2023
-16.7%YoY
Recombinant Protein & Peptide Therapeutics

Development and application of therapeutic proteins or peptides produced through recombinant DNA technology, including fusion proteins and modified growth factors.

Therapeutic Activity (Pharma)
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14since 2023
0.0%YoY
Electronic Component Bondingfiltered

Specialized welding or bonding techniques and apparatuses tailored for joining small-scale electronic components, integrated circuits, or semiconductor wafers, emphasizing precision, miniaturization, and electrical connectivity.

Welding & Soldering
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14since 2023
-77.8%YoY
Immune Checkpoint Modulation

Therapeutic interventions that target immune checkpoint pathways to either enhance or suppress immune responses, often used in cancer immunotherapy or autoimmune diseases.

Therapeutic Activity (Pharma)
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13since 2023
+25.0%YoY
AI for Medical Diagnostics

Utilizing machine learning, particularly deep learning, to analyze medical data such as images, sensor readings, or physiological signals for disease prediction, diagnosis, or treatment assessment.

Medical Diagnostics & SurgeryImage ProcessingHealthcare Informatics
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13since 2023
-40.0%YoY
Physiological Monitoring & Diagnostics

Systems and methods for non-invasive or minimally invasive collection and analysis of physiological data (e.g., blood pressure, electrolytes, genetic markers, B cell repertoire) to assess patient health status, screen for conditions, or aid in diagnosis.

Healthcare Informatics
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13since 2023
-66.7%YoY
Advanced Optical Imaging & Lens Design

Development of sophisticated optical lens assemblies and computational methods to achieve high-resolution, precise, or specialized imaging, often for medical or scientific applications.

Optical Elements & Systems
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12since 2023
+200.0%YoY
Targeted Drug Formulation Delivery

Delivery systems specifically engineered to administer advanced drug formulations (e.g., microparticles, biologics, extended-release systems) to achieve precise targeting, controlled release kinetics, or enhanced therapeutic efficacy within the body.

Pharmaceutical Preparations
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10since 2023
-33.3%YoY
Advanced Solder & Flux Formulations

Development of novel chemical compositions for fluxes, solders, and filler metals to improve material properties, enhance joint reliability, reduce defects, or meet specific application requirements like high-temperature reflow or specialized material joining.

Welding & Soldering
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9since 2023
-50.0%YoY
LED Epitaxial Layer Engineering

Development and optimization of the semiconductor material layers and their interfaces within an LED to control light emission properties, manage internal stress, and improve device efficiency.

LED & Optoelectronics (Legacy CPC)
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9since 2023
-25.0%YoY
Automated Visual Inspection

Systems that employ imaging and image processing to automatically detect defects, verify states, or ensure quality control in manufactured goods, printed materials, or industrial processes.

Material & Chemical Analysis
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8since 2023
+50.0%YoY
Wearable Physiological Sensing

Development of devices and methods for non-invasive or minimally invasive collection and analysis of physiological data, often from wearable sensors, to monitor health, activity, or specific conditions.

Medical Diagnostics & Surgery
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8since 2023
n/a
Interventional & Implantable Therapies

Design and application of devices that are inserted into the body or implanted to treat diseases, modulate physiological functions, or repair anatomical structures.

Medical Diagnostics & Surgery
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6since 2023
new
Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
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6since 2023
-50.0%YoY
Weld Quality Monitoring & NDT

Systems and methods for assessing the quality and characteristics of welds or solder joints, often involving non-destructive testing (NDT) techniques, image processing, or real-time feedback for process control and defect detection.

Welding & Soldering
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5since 2023
-50.0%YoY
Micro-LED Array Fabrication

Methods and structures for mass-producing and assembling arrays of micro-LEDs onto a substrate, including transfer processes, bonding techniques, and defect management.

LED & Optoelectronics (Legacy CPC)
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4since 2023
+200.0%YoY
Video Enhancement & Object Tracking

Methods and systems for improving the quality of video streams, generating intermediate frames, or continuously locating and following objects within a sequence of images, even under occlusion.

Image Processing
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4since 2023
+100.0%YoY
Surgical Instrument Mechanisms

Focuses on the mechanical design, articulation, and actuation of hand-held or robotic surgical instruments, including improvements in stapling, cutting, grasping, and tissue manipulation.

Medical Diagnostics & Surgery
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4since 2023
0.0%YoY
OLED Emitter Materials

Development and optimization of organic chemical compounds and their structures, including guest-host systems and metal complexes, used within the emission layer to achieve specific light emission characteristics such as color, efficiency, and operational lifetime.

Functional Materials (LCD, Lubricants)
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3since 2023
new
Smart Medication Management

Systems that integrate digital technology, sensors, or connectivity to monitor, track, or automate aspects of medication administration, often providing data feedback, personalized recommendations, or secure logging.

Healthcare Informatics
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3since 2023
0.0%YoY
Laser Material Processing

Techniques and systems utilizing laser beams for precise material modification, including cutting, cladding, ablation, and surface treatment, often for joining, shaping, or removing material.

Welding & Soldering
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3since 2023
n/a
Chemical Synthesis of Drug Intermediates

Processes and methodologies for the efficient and scalable preparation of complex heterocyclic compounds and their precursors, including specific reaction conditions, purification techniques, and intermediate compounds.

Heterocyclic Compounds (Pharma)
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2since 2023
n/a
Deep Ultraviolet LED Technology

Specialized design and fabrication of light-emitting diodes specifically engineered to produce light in the deep ultraviolet (DUV) spectrum, often for applications like sterilization or curing.

LED & Optoelectronics (Legacy CPC)
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2since 2023
n/a
Personalized Digital Therapeutics

Digital platforms and systems that deliver tailored therapeutic interventions, guidance, or recommendations to patients based on their individual health data, biometric feedback, and computational models (e.g., AI/ML, physiological simulations).

Healthcare Informatics
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2since 2023
n/a
Surgical Imaging & Navigation

Systems and methods that use imaging technologies, computer vision, and augmented reality to provide real-time guidance, localization, and visualization during surgical procedures or for detailed anatomical assessment.

Medical Diagnostics & Surgery
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1since 2023
n/a
3D Reconstruction & Modeling

Processes for creating or manipulating three-dimensional digital representations of objects or environments, including mesh generation, surface fitting, and depth estimation from multiple views.

Image Processing
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1since 2023
n/a

Patents

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US 20240293888 A1APPLICATION
B23K11/00

DISSIMILAR MATERIAL SOLID-PHASE BONDING METHOD AND DISSIMILAR MATERIAL SOLID-PHASE BONDED STRUCTURE

Filed:2022-03-01Pub:2024-09-05
Applicant:OSAKA UNIVERSITY

The present invention provides dissimilar material solid-phase bonding that efficiently forms a robust bonded portion of metal materials having different compositions and/or structures. The present invention is a solid-phase bonding method in which one member is brought into contact with another member to form an interface to be bonded, and a bonding load is applied, thereby forming newly-generated surfaces of the one member and the other member at the interface to be bonded, wherein the one member and the other member are brought into contact to form the interface to be bonded, the temperature of the interface to be bonded is raised using ohmic heating by running current from the one member to the other member, the one member and the other member are combined while having different electrical resistances, the temperature (T 1 ) of the one member and the temperature (T 2 ) of the other member in the vicinity of the interface to be bonded are set so as to differ from one another, the one member and the other member have approximately the same strength at the temperature (T 1 ) of the one member and the temperature (T 2 ) of the other member, and a bonding load for which a bonding pressure corresponding to said strength is applied is set substantially perpendicular to the interface to be bonded.