Company patents

Repligen Corporation

Repligen Corporation's patent strategy appears to be undergoing a significant shift, with a notable decline across its historically strong categories. While Separation Processes (Filtration, Distillation) still constitutes 41.5% of its portfolio, it has seen a consistent decline, including a -25.0% YoY drop so far in 2026, and Bioreactors / Cell Culture Apparatus, representing 35.4% of its portfolio, has seen a dramatic -100.0% YoY decline in 2026, indicating a potential re-evaluation of core R&D focus.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

65 US filings (since 2023) · 12 categories · 23 themes

Industrial & Bioprocess Filtration

Membrane and depth filtration for industrial separation, gas purification, and bioprocess clarification including cross-flow, dead-end, tangential flow filtration, and oil/water separation.

Bioreactors / Cell Culture ApparatusSeparation Processes (Filtration, Distillation)
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19since 2023
-20.0%YoY
Spectroscopic Material & Process Analysis

Techniques and apparatus utilizing various spectroscopy methods (e.g., Raman, NIRS, photometric, interferometric) for identifying substances, measuring concentrations, or monitoring chemical and physical processes in industrial, environmental, or laboratory settings.

Photometry / Spectrometry
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10since 2023
new
Bioprocess Development for Proteins

Methods and systems for the efficient and scalable production, purification, and formulation of proteins and peptides, including fermentation, chromatography, and cell-based expression systems.

Peptides & Proteins
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10since 2023
+200.0%YoY
Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
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8since 2023
+200.0%YoY
Advanced Valve Actuation

Mechanisms and control systems for precisely moving valve elements, often involving electric motors, cams, solenoids, or pneumatic/hydraulic pilots, to achieve desired flow or position.

Valves
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7since 2023
0.0%YoY
Hydraulic & Pneumatic Control Valves

Valves specifically designed for managing fluid power in hydraulic or pneumatic systems, including components for pressure regulation, flow direction, and system centering.

Valves
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6since 2023
+50.0%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Peptides & Proteins
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6since 2023
+200.0%YoY
Valves for Sanitary & HVAC Systems

Specialized valve designs for domestic and commercial applications involving water distribution, temperature control, and air conditioning, often focusing on integration, materials, and specific flow characteristics.

Valves
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6since 2023
-33.3%YoY
Specialized Fluid Handling Connectionsfiltered

Couplings and fittings designed for specific fluid properties (e.g., cryogenic, chemical, medical, high-pressure) or requiring aseptic conditions, low-spill characteristics, or antimicrobial features to ensure safety and integrity.

Pipes & Tubing
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5since 2023
new
Advanced Sealing and Valve Design

Innovations in the design, materials, and maintenance of seals, valves, and related components to improve durability, reduce leakage, and enable specific pump functions like high-pressure operation or automated seal replacement.

Pumps (Positive Displacement)
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5since 2023
+100.0%YoY
Multi-spectral & Hyperspectral Imaging

Systems and methods for acquiring and analyzing image data across multiple discrete spectral bands or a continuous spectrum, often for material characterization, environmental monitoring, or remote sensing applications.

Photometry / Spectrometry
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4since 2023
new
Integrated Actuation and Drive Systems

Methods and components for converting power into mechanical motion to drive pump mechanisms, encompassing electric motors, hydraulic actuators, and specialized motion converters like ball screws or solenoids.

Pumps (Positive Displacement)
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4since 2023
n/a
Portable and Compact Pump Devices

Design and engineering solutions for creating self-contained, mobile, or miniaturized pump systems, often incorporating battery power, ergonomic features, and integrated components for ease of use and transport.

Pumps (Positive Displacement)
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4since 2023
n/a
Pump Control and Efficiency

Techniques and systems for optimizing pump operation, including capacity modulation, energy management, pulsation reduction, and precise fluid dispensing to improve performance and reduce energy consumption.

Pumps (Positive Displacement)
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3since 2023
n/a
Medical Sterilization Technologies

Methods and apparatus for disinfecting or sterilizing medical devices, waste, or environments, often employing radiation, chemical agents, or thermal processes, and including monitoring systems.

Sterilization & Biocompatible Materials
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3since 2023
n/a
Integrated Functionality in Tubing

Tubes, hoses, or ducts incorporating additional components or features beyond simple fluid conveyance, such as embedded electronics (sensors, heaters), structural reinforcement, or segregated compartments for cable routing.

Pipes & Tubing
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2since 2023
new
Multi-material Product Integration & Finishing

Techniques for combining multiple materials or layers, often with specialized surface treatments, coatings, or assembly methods, to create functional or aesthetically enhanced plastic articles, including consumer goods and encapsulated electronics.

Plastics Shaping & Molding
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2since 2023
new
Pressure Relief and Check Valves

Valves engineered to automatically open or close based on pressure differentials, preventing over-pressurization, controlling flow direction, or suppressing backflow in fluid systems.

Valves
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2since 2023
n/a
Water Contaminant Remediation

Systems and methods specifically engineered for removing pollutants and impurities from water sources, ranging from groundwater decontamination to point-of-use filtration, often employing adsorption, membrane, or distillation techniques.

Separation Processes (Filtration, Distillation)
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1since 2023
new
Automated Bioreactor Control

Systems and methods for automated monitoring and dynamic adjustment of environmental parameters (e.g., pH, temperature, oxygen, nutrients) and fluid handling within bioreactors to optimize cell/tissue growth or product synthesis.

Bioreactors / Cell Culture Apparatus
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1since 2023
n/a
Bioreactor System Architecture

Innovations in the physical design and modularity of bioreactor vessels and associated components, focusing on improved handling, scalability, perfusion, or integration within larger systems.

Bioreactors / Cell Culture Apparatus
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1since 2023
n/a
Integrated Valve Sensing & Diagnostics

Incorporating sensors and processing capabilities directly into valve systems to monitor operational state, detect malfunctions, measure flow parameters, or verify proper installation.

Valves
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1since 2023
n/a
Advanced Optical Sensor Components

Innovations in the physical design, materials, fabrication, or packaging of photodetectors and optical sensor elements, including thermoelectric, NIR-compliant, and self-mixing interference types, to improve performance or integration.

Photometry / Spectrometry
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1since 2023
n/a

Patents

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