Company patents

Roche Diagnostics Operations, Inc.

Roche Diagnostics Operations, Inc. surprisingly shows a strong emerging focus in Computer Security, with patent filings increasing by 150.0% year-over-year in 2026 (so far), despite its core Material & Chemical Analysis category, representing 69.1% of its portfolio, experiencing a significant decline of 18.0% in 2025 and 64.6% so far in 2026.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

447 US filings (since 2023) · 12 categories · 21 themes

Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
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236since 2023
-30.9%YoY
Integrated Molecular Diagnostic Systems

Self-contained or modular devices designed to automate and integrate multiple steps of molecular diagnostic assays, from sample preparation to result interpretation, often for point-of-care or high-throughput applications.

Laboratory ApparatusGenetic & Microbiological Assays
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143since 2023
-29.4%YoY
Automated Liquid Handling

Systems and components designed for precise, automated manipulation, transfer, and dispensing of liquid samples and reagents, often involving pipettes, robotic arms, and specialized sample containers.

Laboratory Apparatus
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114since 2023
+2.9%YoY
Physiological Monitoring & Diagnostics

Systems and methods for non-invasive or minimally invasive collection and analysis of physiological data (e.g., blood pressure, electrolytes, genetic markers, B cell repertoire) to assess patient health status, screen for conditions, or aid in diagnosis.

Healthcare Informatics
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36since 2023
-41.7%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Material & Chemical AnalysisPeptides & Proteins
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24since 2023
-11.1%YoY
Smart Medication Management

Systems that integrate digital technology, sensors, or connectivity to monitor, track, or automate aspects of medication administration, often providing data feedback, personalized recommendations, or secure logging.

Healthcare Informatics
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21since 2023
-70.0%YoY
Molecular Biomarkers for Disease

Identification and measurement of specific nucleic acid sequences (DNA, RNA), their expression levels, or epigenetic modifications (e.g., methylation) as indicators for disease presence, progression, risk, or treatment response.

Genetic & Microbiological Assays
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20since 2023
+100.0%YoY
Ion Implantation Control & Metrology

Methods and apparatus for precise wafer positioning, ion beam uniformity, and dose monitoring during ion implantation processes in semiconductor device manufacturing.

Electron / Ion Tubes & Discharge
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10since 2023
+200.0%YoY
AI for Medical Diagnostics

Utilizing machine learning, particularly deep learning, to analyze medical data such as images, sensor readings, or physiological signals for disease prediction, diagnosis, or treatment assessment.

Healthcare InformaticsImage ProcessingComputer Vision
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10since 2023
+33.3%YoY
Bioprocess Development for Proteins

Methods and systems for the efficient and scalable production, purification, and formulation of proteins and peptides, including fermentation, chromatography, and cell-based expression systems.

Peptides & Proteins
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10since 2023
+50.0%YoY
Thermal Control for Bio-Reactions

Apparatus and methods for precisely controlling temperature profiles (heating, cooling, incubation) within laboratory reaction vessels or modules to optimize biochemical processes like gene amplification or protein assays.

Laboratory Apparatus
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9since 2023
+200.0%YoY
Secure Data Sharing & Rights Management

Mechanisms to facilitate the secure exchange of data between different entities or systems while enforcing usage policies, managing digital content rights, and ensuring data consistency during replication or transfer.

Computer Security
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6since 2023
+100.0%YoY
Automated Visual Inspection

Systems that employ imaging and image processing to automatically detect defects, verify states, or ensure quality control in manufactured goods, printed materials, or industrial processes.

Material & Chemical Analysis
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6since 2023
+100.0%YoY
Rapid Isothermal Amplification

Methods and kits for amplifying nucleic acids at a constant temperature, enabling faster results and point-of-care applications, often used for pathogen or contamination detection.

Genetic & Microbiological Assays
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6since 2023
n/a
Microfluidic Lab-on-Chip Devices

Miniaturized devices that manipulate small volumes of fluids (nanoliters to picoliters) through microchannels to perform laboratory functions like mixing, separation, reaction, and detection on a single chip.

Laboratory Apparatus
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5since 2023
+100.0%YoY
Secure Data Storage & Provenance

Techniques for protecting data at rest or in backup, ensuring its integrity, confidentiality, and verifiable origin, often involving encryption, unique identifiers, or secure repositories.

Computer SecurityNetwork Security & Access Control
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4since 2023
+100.0%YoY
Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
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4since 2023
0.0%YoY
Immunomodulatory Protein Design

Design and engineering of proteins or peptides to directly modulate immune responses, including enhancing antigen presentation, suppressing inflammation, or activating specific immune cell types.

Peptides & Proteins
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3since 2023
new
Targeted Small Molecule Therapeutics

Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.

Heterocyclic Compounds (Pharma)
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3since 2023
+100.0%YoY
Wearable Physiological Sensing

Development of devices and methods for non-invasive or minimally invasive collection and analysis of physiological data, often from wearable sensors, to monitor health, activity, or specific conditions.

Medical Diagnostics & Surgery
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1since 2023
new
Chemical Synthesis of Drug Intermediates

Processes and methodologies for the efficient and scalable preparation of complex heterocyclic compounds and their precursors, including specific reaction conditions, purification techniques, and intermediate compounds.

Heterocyclic Compounds (Pharma)
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1since 2023
n/a

Patents

Showing 31-40 of 745

Page 4 of 75
US 12555760 B2GRANTED
H01J49/00

Method for optimizing a parameter setting of at least one mass spectrometry device

Filed:2023-06-12Pub:2026-02-17
Applicant:Roche Diagnostics Operations, Inc.

A method for optimizing at least one parameter setting of at least one mass spectrometry device ( 110 ) operating at unit resolution is disclosed. The method comprises the following steps: a) determining at least one analyte detection window for detecting an analyte of interest with the mass spectrometry device ( 110 ), wherein the analyte detection window is defined by a central mass to charge ratio value of the analyte and a predefined width, wherein the central mass to charge ratio value of the analyte is set to a theoretical mass to charge ratio value of the analyte of interest having more than one decimal place and/or a mass to charge ratio value of the analyte of interest determined by a high resolution mass spectrometry measurement having more than one decimal place; b) determining at least one internal standard detection window for detecting an internal standard substance with the mass spectrometry device ( 110 ), wherein the internal standard detection window is defined by a central mass to charge ratio value of the internal standard substance and the pre-defined width, wherein the central mass to charge ratio value of the internal standard substance is set to a mass to charge ratio value of the internal standard substance calculated relative to the analyte of interest and having more than one decimal place and/or to a mass to charge ratio value of the internal standard substance determined by a high resolution mass spectrometry measurement having more than one decimal place.