Company patents

Sanofi

Sanofi's patent strategy surprisingly leans heavily into medical devices, with 'Drug Delivery Devices' making up 52.1% of its portfolio, significantly more than any pharma-biotech category. While most categories saw strong growth in 2024, the sharp declines across the board so far in 2026, including a -74.6% drop in 'Drug Delivery Devices' and a -100.0% drop in 'Machine Learning & AI', suggest a potential re-evaluation or shift in patenting focus.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

772 US filings (since 2023) · 12 categories · 26 themes

Automated Injector Mechanisms

Mechanical or electromechanical systems designed for precise, often self-administered, delivery of medicaments, including features for dose setting, needle insertion/retraction, and safety mechanisms to prevent premature activation.

Drug Delivery Devices
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359since 2023
+2.6%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Peptides & ProteinsPharmaceutical PreparationsTherapeutic Activity (Pharma)Material & Chemical Analysis
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112since 2023
-8.3%YoY
Smart Medication Management

Systems that integrate digital technology, sensors, or connectivity to monitor, track, or automate aspects of medication administration, often providing data feedback, personalized recommendations, or secure logging.

Healthcare Informatics
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102since 2023
-45.0%YoY
Immunomodulatory Protein Design

Design and engineering of proteins or peptides to directly modulate immune responses, including enhancing antigen presentation, suppressing inflammation, or activating specific immune cell types.

Peptides & Proteins
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85since 2023
+3.6%YoY
Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
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71since 2023
+15.8%YoY
Targeted Small Molecule Therapeutics

Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.

Heterocyclic Compounds (Pharma)Pharmaceutical PreparationsAcyclic / Carbocyclic Compounds
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70since 2023
-10.0%YoY
Recombinant Protein & Peptide Therapeutics

Development and application of therapeutic proteins or peptides produced through recombinant DNA technology, including fusion proteins and modified growth factors.

Therapeutic Activity (Pharma)
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46since 2023
0.0%YoY
Targeted Drug Formulation Delivery

Delivery systems specifically engineered to administer advanced drug formulations (e.g., microparticles, biologics, extended-release systems) to achieve precise targeting, controlled release kinetics, or enhanced therapeutic efficacy within the body.

Drug Delivery DevicesPharmaceutical Preparations
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43since 2023
-8.3%YoY
Targeted Protein Degradation

Development of small molecules, often bifunctional (e.g., PROTACs) or molecular glues, that induce the ubiquitin-proteasome system or autophagy to selectively degrade specific disease-causing proteins.

Heterocyclic Compounds (Pharma)
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32since 2023
-30.0%YoY
Nucleic Acid-Based Therapies

Therapeutic strategies employing nucleic acids (DNA, RNA, oligonucleotides) to modulate gene expression, deliver genetic material, or interfere with disease-causing pathways. Includes gene therapy using viral vectors.

Pharmaceutical PreparationsTherapeutic Activity (Pharma)
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28since 2023
-25.0%YoY
Advanced Cell & Gene Therapies

Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.

Pharmaceutical PreparationsPeptides & Proteins
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27since 2023
-66.7%YoY
Bioprocess Development for Proteins

Methods and systems for the efficient and scalable production, purification, and formulation of proteins and peptides, including fermentation, chromatography, and cell-based expression systems.

Peptides & Proteins
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16since 2023
-50.0%YoY
AI for Medical Diagnostics

Utilizing machine learning, particularly deep learning, to analyze medical data such as images, sensor readings, or physiological signals for disease prediction, diagnosis, or treatment assessment.

Machine Learning & AIHealthcare InformaticsMedical Diagnostics & SurgeryImage ProcessingComputer Vision
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15since 2023
+40.0%YoY
Immune Checkpoint Modulation

Therapeutic interventions that target immune checkpoint pathways to either enhance or suppress immune responses, often used in cancer immunotherapy or autoimmune diseases.

Therapeutic Activity (Pharma)
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14since 2023
+300.0%YoY
Physiological Monitoring & Diagnostics

Systems and methods for non-invasive or minimally invasive collection and analysis of physiological data (e.g., blood pressure, electrolytes, genetic markers, B cell repertoire) to assess patient health status, screen for conditions, or aid in diagnosis.

Healthcare Informatics
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14since 2023
-40.0%YoY
Advanced Drug Delivery Systems

Development of lipid-based nanoparticles, liposomes, or other molecular platforms to encapsulate and deliver therapeutic agents, particularly nucleic acids, to target tissues or improve pharmacokinetics.

Acyclic / Carbocyclic Compounds
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14since 2023
-50.0%YoY
Chemical Synthesis of Drug Intermediates

Processes and methodologies for the efficient and scalable preparation of complex heterocyclic compounds and their precursors, including specific reaction conditions, purification techniques, and intermediate compounds.

Heterocyclic Compounds (Pharma)
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11since 2023
-80.0%YoY
Interventional & Implantable Therapies

Design and application of devices that are inserted into the body or implanted to treat diseases, modulate physiological functions, or repair anatomical structures.

Medical Diagnostics & Surgery
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7since 2023
0.0%YoY
Cellular Immunotherapy

Therapeutic approaches involving the use of living cells, often genetically modified or ex vivo activated, to treat diseases, particularly cancer, by modulating immune responses or replacing damaged cells.

Therapeutic Activity (Pharma)
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6since 2023
+50.0%YoY
Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
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6since 2023
-66.7%YoY
Personalized Digital Therapeutics

Digital platforms and systems that deliver tailored therapeutic interventions, guidance, or recommendations to patients based on their individual health data, biometric feedback, and computational models (e.g., AI/ML, physiological simulations).

Healthcare Informatics
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5since 2023
n/a
API Solid Form Engineering

Techniques for preparing and characterizing specific solid forms, such as crystal forms, salts, co-crystals, or amorphous forms, of active pharmaceutical ingredients to optimize properties like stability, solubility, and bioavailability.

Heterocyclic Compounds (Pharma)
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2since 2023
new
Wearable Physiological Sensing

Development of devices and methods for non-invasive or minimally invasive collection and analysis of physiological data, often from wearable sensors, to monitor health, activity, or specific conditions.

Medical Diagnostics & Surgery
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2since 2023
new
Vision-Based Object & Pose Estimation

Methods and apparatus for detecting objects and determining their three-dimensional position and orientation (pose) using imagery or point cloud data, often for navigation, surveying, or environmental understanding.

Computer Vision
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1since 2023
new
Catheter-based Intervention Devices

Minimally invasive medical devices, typically flexible tubes, inserted into body lumens to deliver substances, remove obstructions, or perform localized treatments like ablation, dialysis, or drainage.

Drug Delivery Devices
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1since 2023
n/a
Video Enhancement & Object Tracking

Methods and systems for improving the quality of video streams, generating intermediate frames, or continuously locating and following objects within a sequence of images, even under occlusion.

Image Processing
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1since 2023
n/a

Patents

Showing 1-10 of 1125

Page 1 of 113
US 12662525 B2GRANTED
C07K16/00

Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains

Filed:2021-08-23Pub:2026-06-23
Applicant:Ablynx N.V.

This invention provides, and in certain specific but non-limiting aspects relates to: assays that can be used to predict whether a given ISV will be subject to protein interference as described herein and/or give rise to an (aspecific) signal in such an assay (such as for example in an ADA immunoassay). Such predictive assays could for example be used to test whether a given ISV could have a tendency to give rise to such protein interference and/or such a signal; to select ISV's that are not or less prone to such protein interference or to giving such a signal; as an assay or test that can be used to test whether certain modification(s) to an ISV will (fully or partially) reduce its tendency to give rise to such interference or such a signal; and/or as an assay or test that can be used to guide modification or improvement of an ISV so as to reduce its tendency to give rise to such protein interference or signal; methods for modifying and/or improving ISV's to as to remove or reduce their tendency to give rise to such protein interference or such a signal; modifications that can be introduced into an ISV that remove or reduce its tendency to give rise to such protein interference or such a signal; ISV's that have been specifically selected (for example, using the assay(s) described herein) to have no or low(er)/reduced tendency to give rise to such protein interference or such a signal; modified and/or improved ISV's that have no or a low(er)/reduced tendency to give rise to such protein interference or such a signal.