THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC)

The present disclosure relates to a step-down power converter including a first switch electrically connected between an input terminal and a first node, a second switch electrically connected between the first node and a second node, a third switch electrically connected between the second node and a switching node, a fourth switch electrically connected between the switching node and a ground node, a first capacitor electrically connected between the first node and the switching node, and a second capacitor electrically connected between the second node and the ground node.

Disclosed are novel decursin derivatives, methods for preparing the same, and anti-inflammatory compositions comprising the same as active ingredients. The decursin derivative is represented by Chemical Formula: X represents —C(═O)—, —C(═O)NH—, or a direct bond; R 1 is —(CH═CH)—R 2 , —(CH 2 ) n —R 3 , or —(CH 2 CH 2 O) m —R 4 ; n is an integer of 0 to 8, and m is an integer of 1 to 3; R 2 , R 3 , and R 4 are each independently CH 3 , C3-C6 cycloalkyl, 5- to 6-membered heterocycloalkyl, C6-C12 aryl, C4-C12 heteroaryl, 1,4-naphthoquinonyl, —CH═CH—R 5 , —S—R 6 , or —S(═O)—R 7 ; R 5 , R 6 , and R 7 are each independently C6-C12 aryl, C4-C12 heteroaryl, or 1,4-naphthoquinonyl; and R 2 , R 3 , R 4 , R 5 , R 6 , and R 7 may each independently be unsubstituted or substituted with a substituent.

The present invention pertains to: a sustained-release PLGA microsphere containing GS-441524; and a method for producing same. Specifically, a microsphere for sustained release within 1 week is produced by encapsulating GS-441524 in a PLGA microsphere, and thus active ingredients can be supplied stably and continuously to improve patients' medication compliance and reduce the burden of drug costs.

The present disclosure relates to a composition including a mango extract and more preferably a solvent extract of mango leaves as an active ingredient for alleviation, suppression, prevention, or treatment of hair loss, and a preparation method therefor. The mango extract according to the present disclosure can be used in a pharmaceutical composition, a food composition, or a cosmetic composition useful for alleviation, suppression, prevention, and treatment of hair loss.

Disclosed are an electrolytic solution for lithium secondary batteries capable of improving lifespan characteristics of a lithium secondary battery under a high voltage condition and a lithium secondary battery including the same. The electrolytic solution may includes a lithium salt, a solvent, and a functional additive. In particular, the functional additive includes a high-voltage additive including a first high-voltage additive, e.g., hexafluoroglutaric anhydride, and a second high-voltage additive, e.g., fluoroethylene carbonate.

The present disclosure provides a method for manufacturing a transparent ultra-thin film including the steps of (a) supplying different PUA precursors to two silicon masters, respectively, and then curing the PUA precursors by irradiation with ultraviolet ray, (b) separating a PUA mold formed by curing the different PUA precursors from the two silicon masters, (c) supplying perfluoropolyether (PFPE) precursor between the PUA molds, and then curing the PEPE precursor by irradiation with the ultraviolet ray, and (d) separating the PUA mold to prepare an ultra-thin film in which the PFPE precursor is cured, and a transparent ultra-thin film manufactured thereby.

Disclosed are an anode-free type lithium secondary battery including liquid metal particles and a polymer electrolyte and a method of manufacturing the same.

There is provided an adversarial self-supervised learning method for a sigma delta modulation device. The device comprises a loop filter including an operational amplifier, and a circuit including a plurality of capacitors, a plurality of resistors, and a plurality of switches, which are connected to the operational amplifier; a quantization part quantizing and outputting a signal that is output from the loop filter; a feed-back converter converting a digital signal output from the quantization part into an analog signal; a memory configured to store one or more instructions; and a processor configured to control turn on or off of the plurality of switches, and adjust resistor values in an equivalent circuit of the loop filter in order to compensate a notch frequency reduced in the loop filter for satisfying a second-order transfer function.

A battery risk assessment device for a battery module including a plurality of battery cells, including a data measurement unit configured to generate sensing data corresponding to the battery module; a deviation calculator configured to: calculate diffusion resistance data of the plurality of battery cells by using a Thevenin equivalent circuit of the battery module, and calculate deviation information based on the sensing data and the diffusion resistance data, wherein the deviation information indicates at least one from among a voltage deviation of the plurality of battery cells, a temperature deviation of the plurality of battery cells, and a diffusion resistance deviation of the plurality of battery cells; and a risk assessment unit configured to determine a battery risk state based on the deviation information.

The present disclosure relates to a recombinant protein comprising a food and mouth disease virus (FMDV) virus like particle (VLP) and a fragment crystallizable region (Fc) of a swine-derived immunoglobulin linked to the surface of the VLP, and a vaccine composition comprising the recombinant protein. The recombinant protein of the present disclosure may form a self-assembling structure including a virus-like particle using a protein derived from a capsid protein of FMDV, which is an antigenic protein, and a swine Fc protein located on the surface of the virus-like particle, and by using a vaccine composition including the recombinant protein, a specific antibody against FMDV may be effectively produced.