Company patents
Thomas Jefferson University
THOMAS JEFFERSON UNIVERSITY demonstrates a strong and consistent focus on "Pharmaceutical Preparations," which constitutes 44.2% of its patent portfolio, showing steady growth in 2024 (+30.8%) and 2025 (+11.8%) before a partial year decline in 2026. Surprisingly, despite a broad medical focus, "Material & Chemical Analysis" has seen a significant decline in priority, with a -75.0% YoY drop in 2025 and no patents so far in 2026, indicating a shift away from this area.
Patent Trend by Technology Area
Yearly patent publications since 2023
Product themes
Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.
120 US filings (since 2023) · 12 categories · 26 themes
Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.
Therapeutic strategies employing nucleic acids (DNA, RNA, oligonucleotides) to modulate gene expression, deliver genetic material, or interfere with disease-causing pathways. Includes gene therapy using viral vectors.
Design and engineering of proteins or peptides to directly modulate immune responses, including enhancing antigen presentation, suppressing inflammation, or activating specific immune cell types.
Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.
Development of small molecules, often bifunctional (e.g., PROTACs) or molecular glues, that induce the ubiquitin-proteasome system or autophagy to selectively degrade specific disease-causing proteins.
Systems and methods that use imaging technologies, computer vision, and augmented reality to provide real-time guidance, localization, and visualization during surgical procedures or for detailed anatomical assessment.
Identification and measurement of specific nucleic acid sequences (DNA, RNA), their expression levels, or epigenetic modifications (e.g., methylation) as indicators for disease presence, progression, risk, or treatment response.
Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.
Systems that provide therapeutic stimulation or field therapy through wearable devices, often incorporating physiological sensing and closed-loop feedback for personalized and adaptive treatment.
Therapeutic application of electrical signals to nerves or tissues to modulate their activity, often using implantable devices, electrodes, and sophisticated programming for various conditions.
Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.
Therapeutic approaches involving the use of living cells, often genetically modified or ex vivo activated, to treat diseases, particularly cancer, by modulating immune responses or replacing damaged cells.
Systems and methods for non-invasive or minimally invasive collection and analysis of physiological data (e.g., blood pressure, electrolytes, genetic markers, B cell repertoire) to assess patient health status, screen for conditions, or aid in diagnosis.
Therapeutic interventions that target immune checkpoint pathways to either enhance or suppress immune responses, often used in cancer immunotherapy or autoimmune diseases.
Design and application of devices that are inserted into the body or implanted to treat diseases, modulate physiological functions, or repair anatomical structures.
Development and application of therapeutic proteins or peptides produced through recombinant DNA technology, including fusion proteins and modified growth factors.
Delivery systems specifically engineered to administer advanced drug formulations (e.g., microparticles, biologics, extended-release systems) to achieve precise targeting, controlled release kinetics, or enhanced therapeutic efficacy within the body.
Development of lipid-based nanoparticles, liposomes, or other molecular platforms to encapsulate and deliver therapeutic agents, particularly nucleic acids, to target tissues or improve pharmacokinetics.
Involves the design and synthesis of semiconductor or perovskite nanocrystals and other nanostructures with tailored optical and electronic properties for advanced applications in light-emitting devices, displays, or quantum technologies.
Assays leveraging CRISPR-Cas systems (e.g., Cas12, Cas13) for highly specific and sensitive detection of target nucleic acids, often involving collateral cleavage activity or reporter molecules.
Use of alternating electric or magnetic fields at specific frequencies and intensities to achieve therapeutic effects, such as inhibiting cell proliferation (e.g., cancer) or modulating cytokine production.
Focuses on the mechanical design, articulation, and actuation of hand-held or robotic surgical instruments, including improvements in stapling, cutting, grasping, and tissue manipulation.
Methods and reagents designed to improve the specificity, efficiency, or yield of nucleic acid capture, ligation, amplification, or library preparation steps, particularly for sequencing applications or quantitative analysis.
Utilizing machine learning, particularly deep learning, to analyze medical data such as images, sensor readings, or physiological signals for disease prediction, diagnosis, or treatment assessment.
Development of devices and methods for non-invasive or minimally invasive collection and analysis of physiological data, often from wearable sensors, to monitor health, activity, or specific conditions.
Systems and devices for delivering gases, aerosols, or pressure support to the respiratory system, often including interfaces like masks and sophisticated control mechanisms for therapeutic effect or airway management.
Patents
Showing 1-10 of 18
Physiological Monitoring & Diagnostics