Company patents

Universite de Lille

Universite de Lille's patent strategy reveals a strong, sustained focus on Pharmaceutical Preparations (29.3% of portfolio) and Therapeutic Activity (Pharma) (24.1% of portfolio), with both categories showing robust growth in 2024 and 2025 before a partial decline so far in 2026. Surprisingly, despite a broad pharma-biotech emphasis, categories like Material & Chemical Analysis and Implants & Prosthetics have seen significant declines, with Material & Chemical Analysis dropping by 100% in 2025 and Implants & Prosthetics by 100% in 2025, indicating a clear shift away from these areas.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

58 US filings (since 2023) · 12 categories · 23 themes

Immunomodulatory Protein Design

Design and engineering of proteins or peptides to directly modulate immune responses, including enhancing antigen presentation, suppressing inflammation, or activating specific immune cell types.

Peptides & Proteins
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5since 2023
0.0%YoY
Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
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5since 2023
n/a
Recombinant Protein & Peptide Therapeutics

Development and application of therapeutic proteins or peptides produced through recombinant DNA technology, including fusion proteins and modified growth factors.

Therapeutic Activity (Pharma)
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4since 2023
new
Targeted Protein Degradation

Development of small molecules, often bifunctional (e.g., PROTACs) or molecular glues, that induce the ubiquitin-proteasome system or autophagy to selectively degrade specific disease-causing proteins.

Heterocyclic Compounds (Pharma)
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4since 2023
+100.0%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Pharmaceutical PreparationsPeptides & ProteinsTherapeutic Activity (Pharma)
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3since 2023
new
Targeted Small Molecule Therapeutics

Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.

Pharmaceutical PreparationsHeterocyclic Compounds (Pharma)
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3since 2023
0.0%YoY
Optical Glass Compositions

Novel glass formulations, often doped with rare-earth elements or specific metal oxides, designed to achieve desired optical properties such as refractive index, light transmittance, polarization, or amplification.

Glass & Glass-Ceramics
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2since 2023
new
Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
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2since 2023
new
Conformal & Selective Film Deposition

Methods for depositing thin films with controlled conformality, thickness, and material properties, including selective deposition on specific areas, often using atomic layer deposition (ALD), chemical vapor deposition (CVD), or epitaxial growth.

Coating & Surface Treatment
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2since 2023
+100.0%YoY
Immune Checkpoint Modulation

Therapeutic interventions that target immune checkpoint pathways to either enhance or suppress immune responses, often used in cancer immunotherapy or autoimmune diseases.

Therapeutic Activity (Pharma)
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2since 2023
0.0%YoY
Medical Device Ergonomics

Focuses on the design of medical equipment for ease of use, mobility, and adaptability in various clinical or home environments, including carts, mounting systems, and compact form factors.

Medical Diagnostics & Surgery
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2since 2023
0.0%YoY
Surgical Instrument Mechanisms

Focuses on the mechanical design, articulation, and actuation of hand-held or robotic surgical instruments, including improvements in stapling, cutting, grasping, and tissue manipulation.

Medical Diagnostics & Surgery
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2since 2023
0.0%YoY
Glass Surface Functionalization

Application of coatings, layers, or chemical treatments to the surface of glass articles to impart specific functionalities such as UV blocking, anti-whitening, hydrophobicity, or adhesion for subsequent layers.

Glass & Glass-Ceramics
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2since 2023
new
Targeted Drug Formulation Delivery

Delivery systems specifically engineered to administer advanced drug formulations (e.g., microparticles, biologics, extended-release systems) to achieve precise targeting, controlled release kinetics, or enhanced therapeutic efficacy within the body.

Pharmaceutical Preparations
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1since 2023
new
Glass-Ceramic Formation

Methods for producing glass-ceramic articles through controlled nucleation and crystallization processes, often involving specific thermal treatments to achieve desired microstructures and properties like strength or dimensional stability.

Glass & Glass-Ceramics
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1since 2023
new
Advanced Cell & Gene Therapies

Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.

Pharmaceutical Preparations
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1since 2023
new
AI for Medical Diagnostics

Utilizing machine learning, particularly deep learning, to analyze medical data such as images, sensor readings, or physiological signals for disease prediction, diagnosis, or treatment assessment.

Medical Diagnostics & Surgery
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1since 2023
new
Nucleic Acid Capture & Prep

Methods and reagents designed to improve the specificity, efficiency, or yield of nucleic acid capture, ligation, amplification, or library preparation steps, particularly for sequencing applications or quantitative analysis.

Genetic & Microbiological Assays
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1since 2023
new
Wearable Physiological Sensing

Development of devices and methods for non-invasive or minimally invasive collection and analysis of physiological data, often from wearable sensors, to monitor health, activity, or specific conditions.

Medical Diagnostics & Surgery
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1since 2023
n/a
Optical Fiber Sensing Systems

Systems and methods that utilize optical fibers as sensing elements or for transmitting sensing signals, often for distributed monitoring of environmental conditions, phase changes, or integrating sensing with communication.

Optical Elements & Systems
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1since 2023
n/a
Molecular Biomarkers for Disease

Identification and measurement of specific nucleic acid sequences (DNA, RNA), their expression levels, or epigenetic modifications (e.g., methylation) as indicators for disease presence, progression, risk, or treatment response.

Genetic & Microbiological Assays
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1since 2023
n/a
Acoustic Wave RF Filters

Devices utilizing piezoelectric materials to generate and filter acoustic waves, often for radio frequency applications, including surface acoustic wave (SAW) and bulk acoustic wave (BAW) structures.

Impedance Networks (Filters, Resonators)
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1since 2023
n/a
Integrated Filter Packaging

Methods and structures for encapsulating, interconnecting, and integrating impedance network components, particularly acoustic filters, into larger modules or systems.

Impedance Networks (Filters, Resonators)
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1since 2023
n/a

Patents

Showing 1-10 of 87

Page 1 of 9
US 20250345794 A1APPLICATION
B01L3/00

DEVICE AND METHOD FOR TRAPPING CELL PAIRS, AND METHOD FOR ANALYSING CELL PAIRS IN REAL TIME

Filed:2023-04-26Pub:2025-11-13
Applicant:CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

The invention relates to a device for trapping at least one cell pair in a solution containing at least one first cell (C 1 ) of a first type and at least one second cell (C 2 ) of a second type, comprising: —a microfluidic channel ( 3 ) adapted for a unidirectional flow (F) of the solution; —a first trap ( 1 ) comprising a pair of first fingers ( 10 a, 10 b ) arranged in the microfluidic channel ( 3 ), at least one of said first fingers ( 10 a, 10 b ) being coupled to a respective first actuator ( 11 a , 11 b ), said first actuator being configured to adjust the first trap ( 1 ) along a direction transversal to the flow (F) between an open position allowing passage of the first cell between the first fingers ( 10 a, 10 b ) and a closed position adapted to a size of the first cell to allow trapping the first cell between the first fingers ( 10 a, 10 b ); 15 —a second trap ( 2 ) comprising a pair of second fingers ( 20 a, 20 b ) arranged in the microfluidic channel ( 3 ), at least one of said second fingers ( 20 a, 20 b ) being coupled to a respective second actuator ( 21 a, 21 b ), said second actuator being configured to adjust the second trap ( 2 ) along a direction transversal to the flow (F) between an open position allowing passage of the second cell between the second fingers ( 20 a, 20 b ) and a closed position adapted to a size of the second cell to allow trapping the second cell between the second fingers ( 20 a, 20 b ); wherein the first trap ( 1 ) is arranged relative to the second trap ( 2 ) so as to form, when the first and second traps are in the closed position, a cell pair comprising the trapped first and second cells such that the second cell is in physical or chemical interaction with the first cell.