Company patents

University of Florida Research Foundation, Inc.

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. demonstrates a broad patent strategy with a significant focus on Pharmaceutical Preparations, comprising 16.3% of its portfolio, despite a recent decline of 31.2% in 2026 so far. Interestingly, while many core pharma and medical device categories show recent declines, Heterocyclic Compounds (Pharma) saw a substantial 125.0% growth in 2024, indicating a dynamic and shifting emphasis within its biotech research, though it too has declined in 2025 and 2026. The sharp declines in Computer Security and Machine Learning & AI, both at -100.0% YoY in 2026 so far, suggest a potential shift away from these computing-related areas.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

404 US filings (since 2023) · 12 categories · 30 themes

Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
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31since 2023
+80.0%YoY
Targeted Small Molecule Therapeutics

Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.

Heterocyclic Compounds (Pharma)Acyclic / Carbocyclic CompoundsPharmaceutical Preparations
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24since 2023
-45.5%YoY
Advanced Cell & Gene Therapies

Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.

Pharmaceutical PreparationsPeptides & Proteins
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15since 2023
-80.0%YoY
Chemical Synthesis of Drug Intermediates

Processes and methodologies for the efficient and scalable preparation of complex heterocyclic compounds and their precursors, including specific reaction conditions, purification techniques, and intermediate compounds.

Heterocyclic Compounds (Pharma)
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10since 2023
-50.0%YoY
Nucleic Acid-Based Therapies

Therapeutic strategies employing nucleic acids (DNA, RNA, oligonucleotides) to modulate gene expression, deliver genetic material, or interfere with disease-causing pathways. Includes gene therapy using viral vectors.

Pharmaceutical PreparationsTherapeutic Activity (Pharma)
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7since 2023
+100.0%YoY
Immunomodulatory Protein Design

Design and engineering of proteins or peptides to directly modulate immune responses, including enhancing antigen presentation, suppressing inflammation, or activating specific immune cell types.

Peptides & Proteins
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7since 2023
-50.0%YoY
Implantable Bio-Stimulation & Sensing

Implantable devices that deliver electrical, optical, or other forms of energy to stimulate tissues or nerves, or sense physiological parameters for therapeutic purposes.

Implants & Prosthetics
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7since 2023
-66.7%YoY
Ophthalmic Surgical Systems

Integrated systems and specialized instruments for performing delicate surgical procedures on the eye, often involving the delivery, manipulation, or monitoring of ophthalmic implants.

Implants & Prosthetics
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7since 2023
n/a
Immune Checkpoint Modulation

Therapeutic interventions that target immune checkpoint pathways to either enhance or suppress immune responses, often used in cancer immunotherapy or autoimmune diseases.

Therapeutic Activity (Pharma)
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6since 2023
new
Novel Catalyst Materials

Development and synthesis of catalysts with unique compositions or structures, such as medium entropy alloys, metal foam-supported catalysts, layered catalytic articles, or high-entropy oxides, to enhance activity, selectivity, or stability in chemical reactions.

Catalysts & Reactors
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6since 2023
+100.0%YoY
Electronic System Layout & Integration

Automated methods and tools for generating, optimizing, and verifying the physical layout and interconnections of electronic components, including integrated circuits, printed circuit boards, and system-level interface protection.

Electronic Design Automation (CAD/EDA)
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6since 2023
new
Targeted Drug Formulation Delivery

Delivery systems specifically engineered to administer advanced drug formulations (e.g., microparticles, biologics, extended-release systems) to achieve precise targeting, controlled release kinetics, or enhanced therapeutic efficacy within the body.

Pharmaceutical Preparations
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6since 2023
-66.7%YoY
Cellular Immunotherapy

Therapeutic approaches involving the use of living cells, often genetically modified or ex vivo activated, to treat diseases, particularly cancer, by modulating immune responses or replacing damaged cells.

Therapeutic Activity (Pharma)
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6since 2023
-50.0%YoY
Digital Twin & System Simulation

Creating virtual models (digital twins) of complex physical systems to simulate their behavior, predict performance, validate designs, or guide operations under various conditions.

Electronic Design Automation (CAD/EDA)
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5since 2023
+700.0%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Therapeutic Activity (Pharma)Peptides & ProteinsPharmaceutical Preparations
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4since 2023
0.0%YoY
Recombinant Protein & Peptide Therapeutics

Development and application of therapeutic proteins or peptides produced through recombinant DNA technology, including fusion proteins and modified growth factors.

Therapeutic Activity (Pharma)
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3since 2023
new
Surgical Imaging & Navigation

Systems and methods that use imaging technologies, computer vision, and augmented reality to provide real-time guidance, localization, and visualization during surgical procedures or for detailed anatomical assessment.

Medical Diagnostics & Surgery
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3since 2023
0.0%YoY
Wearable Physiological Sensing

Development of devices and methods for non-invasive or minimally invasive collection and analysis of physiological data, often from wearable sensors, to monitor health, activity, or specific conditions.

Medical Diagnostics & Surgery
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3since 2023
+100.0%YoY
Interventional & Implantable Therapies

Design and application of devices that are inserted into the body or implanted to treat diseases, modulate physiological functions, or repair anatomical structures.

Medical Diagnostics & Surgery
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2since 2023
+100.0%YoY
Carbon Dioxide Capture & Conversion

Technologies and materials for capturing carbon dioxide from gas streams and subsequently converting it into valuable chemical products or materials, rather than simply storing it.

Catalysts & ReactorsAcyclic / Carbocyclic Compounds
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2since 2023
+100.0%YoY
Component Performance Optimization

Using computational design and simulation to optimize the performance characteristics of specific components or materials within a larger engineering system.

Electronic Design Automation (CAD/EDA)
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2since 2023
0.0%YoY
Industrial Organic Synthesis

Methods and apparatus for the efficient and selective production of organic compounds, including amines, acids, and esters, often involving catalytic or continuous processes and purification steps.

Acyclic / Carbocyclic Compounds
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2since 2023
new
Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
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2since 2023
n/a
Bio-derived Chemical Production

Methods for producing organic chemicals from biomass or through fermentation processes, often focusing on carbohydrates or fatty acid derivatives for food, health, or industrial applications.

Acyclic / Carbocyclic Compounds
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2since 2023
n/a
AI for Medical Diagnostics

Utilizing machine learning, particularly deep learning, to analyze medical data such as images, sensor readings, or physiological signals for disease prediction, diagnosis, or treatment assessment.

Machine Learning & AI
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2since 2023
n/a
Quantum Machine Learning

Developing and applying machine learning algorithms that leverage quantum computing principles, such as quantum circuits or autoencoders, for tasks like simulation or data processing.

Machine Learning & AI
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1since 2023
new
Surgical Instrument Mechanisms

Focuses on the mechanical design, articulation, and actuation of hand-held or robotic surgical instruments, including improvements in stapling, cutting, grasping, and tissue manipulation.

Medical Diagnostics & Surgery
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1since 2023
n/a
Internal Fluid Management Devices

Implantable devices designed to manage or redirect bodily fluids, including stents for ducts, and systems for draining or accumulating fluids within internal cavities.

Implants & Prosthetics
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1since 2023
n/a
Orthopedic & Spinal Implants

Implantable devices used for the fixation, fusion, or replacement of bone structures, particularly in the spine and extremities.

Implants & Prosthetics
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1since 2023
n/a
AI/ML for Cryptographic Security

Applying artificial intelligence and machine learning techniques to enhance cryptographic systems, such as generating encryption models, improving zero-trust architectures, or enabling privacy-preserving computations like federated learning.

Computer Security
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1since 2023
n/a

Patents

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