Wyatt Technology, LLC

Disclosed is a cuvette adapter that includes a body with a chamber for receiving a cuvette and a plurality of openings on an exterior of the body. A plurality of disks are plated with a corrosion-resistant material, and each respective disk of the plurality of disks is positioned in a respective opening of the plurality of openings on the exterior of the body. The disks are configured for providing electrical contact between the cuvette adapter and a light scattering instrument. A system and method for detecting a cuvette adapter are also disclosed.

Systems and methods for controlling sample dilution in an analytical instrument system comprise transmitting an injection command to an autosampler to inject a predetermined volume of air into a sample tubing coupled to an analytical instrument; and transmitting, subsequent to the injection of the predetermined volume of air, a fill command to the autosampler to aspirate a volume of sample into the sample tubing, wherein the predetermined volume of air is configured to form an immiscible barrier between the volume of sample and a solvent within the sample tubing.

The present disclosure describes a field flow fractionator including (a) a top plate assembly including a top electrically conductive electrode, (b) an o-ring, (c) an electrically insulating frit, (d) an electrically insulating spacer between a bottom surface of the top electrode and the o-ring and the frit, (e) a membrane between the spacer and the frit, and (f) a bottom plate assembly including a bottom electrically conductive electrode.

An electrophoretic mobility apparatus comprising a light source, a sample fiberoptic path along which a first source of light including a sample beam travels from the light source, a sample cell along the sample fiberoptic path that receives the first source of light, a reference fiberoptic path along which a second source of light including a reference beam travels from the light source; a lens along the reference fiberoptic path that forms a plane parallel beam from the second source of light; a modulator along the reference fiberoptic path that provides frequency control of the second source of light, a beamsplitter combines the reference beam with a fraction of light scattered from the particles and forms a coherent beam, and a detector comprising an array of photo detector elements onto which the coherent beam is incident, wherein each detector element produces time varying signals from the coherent beam.

A computer implemented method comprises flowing a sample through a sample cell at a flow rate; applying an electric field to the sample while the sample is flowing through the sample cell; and measuring electrophoretic mobility of particles in the sample using light scattering techniques while the sample is flowing and the electric field is applied. The flowing removes degraded sample particles from a measurement region of the sample cell during the measuring and replaces the degraded sample particles with a fresh sample. The flowing removes heat generated by Joule heating from the measurement region. The flowing enables an application of a higher electric field strength, thereby increasing a Doppler shift and reducing measurement time and measurement error.

A system, device, and method for detecting a formation of nanoparticles in a fluid, comprise a temperature controller that provides a temperature of a source of fluid during a temperature ramp cool down operation; a measurement system that detects a particle formation in the source of fluid at an wax particle formation temperature; and an apparatus that detects a cloud point after the particle formation detection by the measurement system and at a temperature less than the wax particle formation temperature, wherein the wax particle formation temperature provides an early warning to users regarding the source of fluid before the fluid becomes visibly cloudy.

The present disclosure describes a computer implemented method, a system, and a computer program product of determining intrinsic viscosity and Huggins constant of an unknown sample. In an embodiment, the method, system, and computer program product include, receiving specific viscosity values over time from a viscometer corresponding to a series of aliquots of an unknown sample injected into an instrument chain where the instrument chain includes the viscometer, calculating a total mass of each of the aliquots, calculating a first intermediate viscosity value of each of the aliquots, calculating a second intermediate viscosity value of each of the aliquots, and fitting the total mass, the first intermediate viscosity value, and the second intermediate viscosity value to a fitting, resulting in a calculated intrinsic viscosity of the unknown sample and a calculated Huggins constant of the unknown sample.

An apparatus comprises a light source; a spherical flow cell having a bore for providing a flow path for a fluid sample and for transmitting light from the light source through the fluid sample in the bore, the bore extending from an input port to a first output port of the spherical flow cell, and for capturing a scattered portion of the light for output through a second output port; a first detector proximal to the first output port for measuring a transmitted light intensity of the light; a second detector proximal to the second output port for measuring a scattered intensity of the light; and a special purpose computer processor that calculates a true absorption value from the measured transmitted light intensity and the measured scattered intensity.

A flow cell comprises a top structure, comprising: a plurality of first fittings at a first side of the top structure; a plurality of second fittings at a second side of the top structure; a plurality of channels extending from the first fittings to the second fittings; a plurality of flow-through cylindrical electrodes extending through the plurality of channels, wherein a distal end of the flow-through cylindrical electrodes is offset from a distal end of the second fittings by a predetermined distance; a bottom structure comprising: a plurality of fitting receptacles constructed and arranged to connect to the second fittings; and a fluid path that extends from one channel of the plurality of channels and one of the second fittings in communication with the one channel to another channel of the plurality of channels and another of the second fittings in communication with the other channel.