Patent Theme

Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

16,125 US filings from 4,223 companies since 2023 · 2023: 3,757 · 2024: 5,339 · 2025: 4,909 · 2026 YTD: 2,120

Pharmaceutical PreparationsTherapeutic Activity (Pharma)Peptides & ProteinsMaterial & Chemical Analysis

Top companies

Ranked by filings in this theme since 2023. 2026 is partial.

#	Company	Since 2023	2023	2024	2025	2026 YTD	YoY
1	Regeneron Pharmaceuticals, Inc.	405	88	136	122	59	-10.3%
2	Hoffmann-La Roche Inc.	314	86	89	95	44	+6.7%
3	Genentech, Inc.	239	60	76	68	35	-10.5%
4	JANSSEN BIOTECH, INC.	193	35	74	63	21	-14.9%
5	Novartis AG	188	49	63	45	31	-28.6%
6	Chugai Seiyaku Kabushiki Kaisha	182	42	62	46	32	-25.8%
7	The Regents of the University of California	181	44	58	47	32	-19.0%
8	AMGEN INC.	167	31	52	60	24	+15.4%
9	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA	136	29	52	37	18	-28.8%
10	Xencor, Inc.	122	32	35	40	15	+14.3%
11	Bristol-Myers Squibb Company	117	33	38	31	15	-18.4%
12	Board of Regents, The University of Texas System	116	27	39	35	15	-10.3%
13	Sanofi	112	24	36	33	19	-8.3%
14	Memorial Sloan Kettering Cancer Center	106	28	37	24	17	-35.1%
15	GENMAB A/S	101	24	37	27	13	-27.0%
16	SEAGEN INC.	97	35	43	15	4	-65.1%
17	TAKEDA PHARMACEUTICAL COMPANY LIMITED	93	23	27	31	12	+14.8%
18	The Board of Trustees of the Leland Stanford Junior University	93	28	29	29	7	0.0%
19	Pfizer Inc.	90	31	34	18	7	-47.1%
20	Daiichi Sankyo Company, Limited	81	19	26	29	7	+11.5%
21	Dana-Farber Cancer Institute, Inc.	68	15	14	26	13	+85.7%
22	City of Hope	66	21	15	18	12	+20.0%
23	Incyte Corporation	65	11	26	19	9	-26.9%
24	UCB BIOPHARMA SRL	64	23	19	18	4	-5.3%
25	ELI LILLY AND COMPANY	61	14	26	11	10	-57.7%