BOLT MEDICAL, INC.

A method for treating a vascular lesion within or adjacent to a vessel wall within a body of a patient by generating a plasma that creates pressure waves adjacent to the vascular lesion, includes the steps of (i) generating light energy in the form of a source beam with a single light source; (ii) positioning a multiplexer in a beam path of the source beam, the multiplexer including an optical element; (iii) receiving the source beam with the optical element of the multiplexer; (iv) splitting the source beam into a first guide beam and a second guide beam with the optical element of the multiplexer; (v) directing the first guide beam to a first light guide with the multiplexer; and (vi) directing the second guide beam to a second light guide with the multiplexer.

A catheter system for treating a vascular lesion within or adjacent to a vessel wall within a body of a patient includes a single light source that generates light energy, a first light guide and a second light guide, and a multiplexer. The first light guide and the second light guide are each configured to selectively receive light energy from the light source. The multiplexer receives the light energy from the light source in the form of a source beam and selectively directs the light energy from the light source in the form of individual guide beams to each of the first light guide and the second light guide.

A catheter system for treating a treatment site includes an energy source, a balloon, an energy guide, and a pressure sensor. The balloon is positionable substantially adjacent to the treatment site. The balloon has a balloon wall that defines a balloon interior that receives a balloon fluid. The energy source generates energy that is received by the energy guide so that the energy guide can guide the light energy into the balloon interior. The pressure sensor senses a balloon pressure of the balloon fluid. A method for disrupting calcification at the treatment site includes the steps of generating energy with an energy source, positioning a balloon substantially adjacent to the treatment site, the balloon having a balloon wall that defines a balloon interior, the balloon interior being configured to receive a balloon fluid, receiving energy from the energy source with an energy guide, guiding the energy from the energy source into the balloon interior with the energy guide; and sensing a balloon pressure of the balloon fluid with a pressure sensor.

A method for manufacturing a catheter ( 102 ) including a rapid exchange port ( 157 ). The method can include the steps of generating a port ( 258 ) in a catheter shaft ( 210 ), inserting a guidewire lumen ( 118 ) into the port ( 258 ), pulling the guidewire lumen ( 118 ) in a proximal direction, and pushing the guidewire lumen ( 118 ) in a distal direction so that the guidewire lumen ( 118 ) is within the catheter shaft ( 210 ). The method can also include the steps of thermally bonding the guidewire lumen ( 118 ) within the catheter shaft ( 210 ), trimming the guidewire lumen ( 118 ) so that a guidewire lumen ( 118 ) proximal end is flush with a catheter shaft ( 210 ) exterior.

A catheter system ( 100 ) usable for treating a treatment site ( 106 ) within or adjacent to a vessel wall ( 108 A) of a blood vessel ( 108 ) or a heart valve within a body ( 107 ) of a patient ( 109 ), the catheter system ( 100 ) can include an energy source ( 124 ) that generates energy, a catheter ( 102 ) that includes an energy guide ( 122 A) that receives the energy from the energy source ( 124 ), and a system controller ( 126 ) that is coupled to the energy source ( 124 ), the system controller ( 126 ) being configured to: (i) monitor real-time operating parameters of the catheter system ( 100 ), including at least energy delivery characteristics and treatment site conditions, (ii) detect and identify operating parameters that require adjustment, (iii) automatically adjust operating parameters, and (iv) dynamically provide a summary of system status, treatment progress, and actionable alerts.

A catheter system ( 100 ) for treating a treatment site ( 106 ) within or adjacent to a blood vessel ( 108 ) includes a power source ( 124 ), a light guide ( 122 ) and a plasma target ( 242 ). In various embodiments, the light guide ( 122 ) receives power from the power source ( 124 ). The light guide ( 122 ) has a distal tip ( 244 ), and the light guide ( 122 ) emits light energy ( 243 ) in a direction away from the distal tip ( 244 ). The plasma target ( 242 ) is spaced apart from the distal tip ( 244 ) of the light guide ( 122 ) by a target gap distance ( 245 ). The plasma target ( 242 ) is configured to receive light energy ( 243 ) from the light guide ( 122 ) so that a plasma bubble ( 234 ) is generated at the plasma target ( 242 ). The power source ( 124 ) can be a laser and the light guide ( 122 ) can be an optical fiber. The catheter system ( 100 ) can also an inflatable balloon ( 104 ) that encircles the distal tip ( 244 ) of the light guide ( 122 ). The plasma target ( 242 ) can be positioned within the inflatable balloon ( 104 ). The plasma target ( 242 ) can have a target face ( 1672 ) that receives the light energy ( 243 ) from the light guide ( 122 ). The plasma target ( 242 ) can be formed from one or more of tungsten, tantalum, platinum, molybdenum, niobium, iridium, magnesium oxide, beryllium oxide, tungsten carbide, titanium nitride, titanium carbonitride and titanium carbide.

A catheter system ( 100 ) for treating a treatment site ( 106 ) within or adjacent to a blood vessel ( 109 ) or a heart valve within the body of a patient includes an energy source ( 124 ), a fiber assembly ( 568 ), and an emitter assembly ( 670 ). The energy source ( 124 ) generates energy. The fiber assembly ( 568 ) receives the energy from the energy source ( 124 ). The fiber assembly ( 568 ) has a proximal cross-section and a distal cross-section. The proximal cross-section has a proximal height ( 550 H) and a proximal width ( 550 W). The distal cross-section has a distal height ( 559 H) and a distal width ( 559 W). The proximal height ( 550 H) is substantially equal to the proximal width ( 550 W). The distal height ( 559 H) is less than the distal width ( 559 W).

A catheter system ( 100 ) for treating a vascular lesion ( 106 A) within or adjacent to a vessel wall ( 108 A) of a blood vessel ( 108 ) within a body ( 107 ) of a patient ( 109 ) includes a catheter shaft ( 210 ); a handle assembly ( 228 ); and a source manifold ( 236 ). The handle assembly ( 228 ) is coupled to the catheter shaft ( 210 ). The handle assembly ( 228 ) includes an assembly housing ( 266 ). The handle assembly ( 228 ) is usable by a user to selectively position the catheter shaft ( 210 ) near the vascular lesion ( 106 A). The source manifold ( 236 ) is coupled to the assembly housing ( 266 ). The source manifold ( 236 ) includes a manifold housing ( 282 ) having a catheter shaft port ( 264 ) that is configured to receive a portion of the catheter shaft ( 210 ) so that the catheter shaft ( 210 ) is coupled to the manifold housing ( 282 ).

Provided is a distal stabilizer capable of more securely and more quickly identifying slack of a delivery wire or a microcatheter and aberrant of the same into a mass. The distal stabilizer 1, which is to be used for delivering a catheter in a biological lumen, comprises: a linear delivery member 3; an anchor device 2 extending from the distal end of the linear delivery member 3 and capable of being engaged to the inner wall of the biological lumen; and a visible part 4 provided on the distal side of the linear delivery member 3 and including a radiopaque part that is bendable in the axial direction together with the linear delivery member 3.

A catheter system ( 100 ) for treating a treatment site ( 106 ) within or adjacent to a blood vessel ( 108 ) includes a power source ( 124 ), a light guide ( 122 ) and a plasma target ( 242 ). In various embodiments, the light guide ( 122 ) receives power from the power source ( 124 ). The light guide ( 122 ) has a distal tip ( 244 ), and the light guide ( 122 ) emits light energy ( 243 ) in a direction away from the distal tip ( 244 ). The plasma target ( 242 ) is spaced apart from the distal tip ( 244 ) of the light guide ( 122 ) by a target gap distance ( 245 ). The plasma target ( 242 ) is configured to receive light energy ( 243 ) from the light guide ( 122 ) so that a plasma bubble ( 234 ) is generated at the plasma target ( 242 ). The power source ( 124 ) can be a laser and the light guide ( 122 ) can be an optical fiber. The catheter system ( 100 ) can also an inflatable balloon ( 104 ) that encircles the distal tip ( 244 ) of the light guide ( 122 ). The plasma target ( 242 ) can be positioned within the inflatable balloon ( 104 ). The plasma target ( 242 ) can have a target face ( 1672 ) that receives the light energy ( 243 ) from the light guide ( 122 ). The plasma target ( 242 ) can be formed from one or more of tungsten, tantalum, platinum, molybdenum, niobium, iridium, magnesium oxide, beryllium oxide, tungsten carbide, titanium nitride, titanium carbonitride and titanium carbide.