Technische Universität Darmstadt

Development of small molecules, often bifunctional (e.g., PROTACs) or molecular glues, that induce the ubiquitin-proteasome system or autophagy to selectively degrade specific disease-causing proteins.

Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.

Tubes, hoses, or ducts incorporating additional components or features beyond simple fluid conveyance, such as embedded electronics (sensors, heaters), structural reinforcement, or segregated compartments for cable routing.

Connectors, seals, and tubing solutions specifically designed for pipes, ducts, or conduits that deviate from standard circular cross-sections, or require flexible/collapsible forms for specific applications or installation challenges.

Systems and methods for repairing, reinforcing, or isolating existing pipes, often involving internal lining, curing processes, or sealing techniques without extensive excavation or replacement.

Integration of electric machines, energy storage, and power transfer systems with gas turbine engines to enable hybrid operation, electric starting, or auxiliary power generation, improving efficiency or operational flexibility.

Addresses the design and arrangement of electric motors, transmissions, and associated power electronics (like inverters) to form integrated drive units for hybrid or electric vehicles, including specific components like busbars and electric brakes.

Utilizing dedicated hardware components, secure enclaves, or trusted execution environments to perform cryptographic operations, enhancing security, performance, or isolation from software vulnerabilities.

Techniques for building three-dimensional metal objects layer-by-layer using metal powders, including powder bed fusion, binder jetting, and directed energy deposition. This theme encompasses process mechanics, equipment design, and operational control for AM systems.

Integration of additive manufacturing with subtractive manufacturing (e.g., machining, cutting) or other traditional processes within a single system or workflow to create parts with improved features, surface finish, or material properties, or to enable new manufacturing paradigms.

Methods and processes for fabricating ceramic matrix composites (CMCs), including preform creation, infiltration techniques, and densification to form complex shapes with enhanced properties.

Focuses on the design, fabrication, and application of piezoelectric materials and devices for sensing, actuation, or wave generation, including material properties, single crystal growth, and protective layers.

Methods and components for converting power into mechanical motion to drive pump mechanisms, encompassing electric motors, hydraulic actuators, and specialized motion converters like ball screws or solenoids.