Company patents

TECHNISCHE UNIVERSITÄT MÜNCHEN

Technische Universität München's patent strategy reveals a strong, consistent focus on 'Pharmaceutical Preparations,' which constitutes 28.5% of its portfolio and saw a 37.5% YoY growth in 2024, indicating sustained investment in this core area despite a partial decline so far in 2026. Surprisingly, while 'Material & Chemical Analysis' represents a significant 13.8% of its portfolio, it has experienced a sharp decline in recent years, with an 80.0% drop in patent filings so far in 2026, suggesting a potential shift in priorities away from this area.

Patent Trend by Technology Area

Yearly patent publications since 2023

Product themes

Product-level themes inferred from filings since 2023, with category chips showing where each theme appears. Select a theme to filter the patents below.

130 US filings (since 2023) · 12 categories · 25 themes

Advanced Biomarker Detection Assays

Methods and compositions for identifying, quantifying, or characterizing specific biological molecules (e.g., nucleic acids, proteins, metabolites, antibodies) or microbial species, often for diagnostic, prognostic, or quality control applications.

Material & Chemical Analysis
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29since 2023
-35.7%YoY
Radiopharmaceutical & Imaging Probes

Compounds, often featuring metal chelators or specific labeling moieties, designed for use in medical imaging techniques like Positron Emission Tomography (PET) or for radionuclide therapy, enabling diagnostic visualization or targeted radiation treatment.

Acyclic / Cyclic Compounds (Other Elements)
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19since 2023
+100.0%YoY
Nucleic Acid-Based Therapies

Therapeutic strategies employing nucleic acids (DNA, RNA, oligonucleotides) to modulate gene expression, deliver genetic material, or interfere with disease-causing pathways. Includes gene therapy using viral vectors.

Pharmaceutical PreparationsTherapeutic Activity (Pharma)
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12since 2023
+66.7%YoY
Targeted Small Molecule Therapeutics

Design and synthesis of acyclic or carbocyclic organic compounds that selectively modulate specific biological targets or pathways for the treatment of diseases.

Pharmaceutical Preparations
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12since 2023
0.0%YoY
Metal Additive Manufacturing Processes

Techniques for building three-dimensional metal objects layer-by-layer using metal powders, including powder bed fusion, binder jetting, and directed energy deposition. This theme encompasses process mechanics, equipment design, and operational control for AM systems.

Plastics Shaping & MoldingAdditive Manufacturing (3D Printing)
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8since 2023
+50.0%YoY
Antibody Engineering & Therapeutics

Design and modification of antibodies or antibody-derived fragments for targeted therapeutic intervention, including bispecific formats, Fc region modifications, and activatable constructs.

Peptides & ProteinsPharmaceutical PreparationsMaterial & Chemical AnalysisTherapeutic Activity (Pharma)
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7since 2023
0.0%YoY
Recombinant Protein & Peptide Therapeutics

Development and application of therapeutic proteins or peptides produced through recombinant DNA technology, including fusion proteins and modified growth factors.

Therapeutic Activity (Pharma)
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7since 2023
new
Bioprocess Development for Proteins

Methods and systems for the efficient and scalable production, purification, and formulation of proteins and peptides, including fermentation, chromatography, and cell-based expression systems.

Peptides & Proteins
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6since 2023
0.0%YoY
Hydrogen Production Catalysis

Catalytic processes and novel catalyst materials designed to efficiently produce hydrogen gas from various feedstocks, including hydrocarbons (e.g., methane, natural gas) and ammonia.

Electrolysis & Electrochemistry
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6since 2023
-50.0%YoY
Electrolyzer Durability & Control

Methods and systems for enhancing the operational lifespan, stability, and performance management of electrolyzers, including strategies for preventing degradation, restoring activity, and regulating operating conditions.

Electrolysis & Electrochemistry
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6since 2023
-75.0%YoY
Protein & Peptide Engineering

Modification of protein or peptide sequences, structures, or post-translational modifications (e.g., glycosylation, lipidation) to enhance their stability, solubility, delivery, or therapeutic efficacy.

Peptides & Proteins
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4since 2023
new
Advanced Cell & Gene Therapies

Development of therapeutic approaches involving the genetic modification of cells (e.g., T cells, stem cells, macrophages) or the use of viral/non-viral vectors to deliver genetic material for disease treatment.

Pharmaceutical PreparationsPeptides & Proteins
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4since 2023
+100.0%YoY
Microfluidic Lab-on-Chip Devices

Miniaturized devices that manipulate small volumes of fluids (nanoliters to picoliters) through microchannels to perform laboratory functions like mixing, separation, reaction, and detection on a single chip.

Laboratory Apparatus
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4since 2023
+100.0%YoY
Immunomodulatory Protein Design

Design and engineering of proteins or peptides to directly modulate immune responses, including enhancing antigen presentation, suppressing inflammation, or activating specific immune cell types.

Peptides & Proteins
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4since 2023
-66.7%YoY
Immune Checkpoint Modulation

Therapeutic interventions that target immune checkpoint pathways to either enhance or suppress immune responses, often used in cancer immunotherapy or autoimmune diseases.

Therapeutic Activity (Pharma)
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4since 2023
-50.0%YoY
CO2 Electroreduction Catalysts

Development of catalytic materials and membrane electrode assemblies (MEAs) specifically designed for the electrochemical reduction of carbon dioxide (CO2) or carbon monoxide (COx) into valuable chemicals or fuels.

Electrolysis & Electrochemistry
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3since 2023
+100.0%YoY
Integrated Molecular Diagnostic Systemsfiltered

Self-contained or modular devices designed to automate and integrate multiple steps of molecular diagnostic assays, from sample preparation to result interpretation, often for point-of-care or high-throughput applications.

Laboratory Apparatus
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3since 2023
-50.0%YoY
Enzyme Directed Evolution

Identifying novel enzymes or modifying existing enzymes through mutagenesis and directed evolution to improve catalytic activity, substrate specificity, or stability for industrial biotransformations.

Fermentation & Biosynthesis
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2since 2023
new
Cellular Immunotherapy

Therapeutic approaches involving the use of living cells, often genetically modified or ex vivo activated, to treat diseases, particularly cancer, by modulating immune responses or replacing damaged cells.

Therapeutic Activity (Pharma)
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2since 2023
0.0%YoY
Electrolyzer Cell Components

Design and engineering of non-catalytic parts within an electrolysis cell or stack, such as separators, gaskets, flow fields, porous transport layers, and manifold devices, to improve efficiency, sealing, or gas management.

Electrolysis & Electrochemistry
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2since 2023
n/a
Recombinant Host Engineering

Modifying microorganisms, plant cells, or animal cells through genetic engineering to enhance or enable the biosynthesis of target compounds, often involving metabolic pathway engineering.

Fermentation & Biosynthesis
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1since 2023
new
Hybrid Additive-Subtractive Manufacturing

Integration of additive manufacturing with subtractive manufacturing (e.g., machining, cutting) or other traditional processes within a single system or workflow to create parts with improved features, surface finish, or material properties, or to enable new manufacturing paradigms.

Additive Manufacturing (3D Printing)
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1since 2023
new
Lithium Battery Anode Materials

Active anode materials and manufacturing techniques for rechargeable lithium-ion batteries, including silicon-carbon composites, graphite, lithium-metal anodes, and electrode coating processes that improve capacity, cycle life, and rate capability.

Batteries & Fuel Cells
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1since 2023
n/a
Battery Electrode Coating & Slurry

Slurry compositions and coating processes for battery electrodes, including binder/active-material slurries, surface coating layers, and electrode-to-foil adhesion for cathode and anode.

Batteries & Fuel Cells
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1since 2023
n/a
Electrochemical Chemical Synthesis

Utilization of electrochemical processes to synthesize a variety of chemical products, materials, or to treat waste streams, by selectively promoting redox reactions of specific feedstocks beyond hydrogen or CO2 reduction.

Electrolysis & Electrochemistry
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1since 2023
n/a

Patents

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US 20250277722 A1APPLICATION
G01N1/28

ANALYSIS OF HETEROGENEOUS CELL/TISSUE SAMPLES USING A MICROFLUIDIC DEVICE

Filed:2022-04-29Pub:2025-09-04
Applicant:TECHNISCHE UNIVERSITÄT MÜNCHEN

A microfluidic device for analyzing a sample comprising one or more sample objects containing biological cells, a method of analyzing a sample comprising one or more sample objects containing biological cells using such a microfluidic device and a system for analyzing a sample comprising one or more sample objects containing biological cells for use with such a microfluidic device. The one or more sample objects comprise one or more single cells, one or more cell aggregates and/or one or more pieces of continuous tissue material. The microfluidic device comprises an insertion volume configured to receive the sample. The microfluidic device further comprises a sorting unit having an inlet that is in fluid communication with the insertion volume, a first outlet and a second outlet. The sorting unit is configured to sort the sample objects by size, weight and/or stiffness by directing sample objects having a smaller size, a smaller weight and a lower stiffness, respectively, from the inlet towards the first outlet and sample objects having a larger size, a larger weight and a higher stiffness, respectively, from the inlet towards the second outlet. The microfluidic device also comprises a measurement volume that is in fluid communication with the first outlet of the sorting unit. The microfluidic device further comprises a dissociation unit comprising means for dissociating sample objects into single cells and/or cell aggregates at least in part. An inlet of the dissociation unit is in fluid communication with the second outlet of the sorting unit and an outlet of the dissociation unit is in fluid communication with an inlet of the measurement volume.

US 20240241105 A1APPLICATION
G01N33/487

PARALLELIZED PROBING OF A PLURALITY OF SAMPLES IN A SELF-ORGANIZED STRUCTURE

Filed:2022-05-17Pub:2024-07-18
Applicant:TECHNISCHE UNIVERSITÄT MÜNCHEN

Disclosed herein is a method for parallelized probing of a plurality of samples, a sensor chip for parallelized probing of a plurality of samples, a sensing device for parallelized probing of a plurality of samples, and a measurement system for parallelized probing of a plurality of samples. The method comprises providing a sensor chip, the sensor chip comprising a sensing layer arranged in or on a substrate and a measurement volume adjacent to the sensing layer. The sensing layer comprises a plurality of sensing elements, each of which is configured to generate a sensor signal characterizing a physical observable in the vicinity of the respective sensing element. A carrier fluid comprising a plurality of sample objects is provided to the measurement volume, wherein each of the sample objects comprises or forms a respective sample. A number of sample objects in the measurement volume is controlled such that the sample objects form a self-organized structure in the measurement volume. The self-organized structure is a structure in which the arrangement of the sample objects is at least in part defined by interactions between the sample objects themselves. A measurement is performed on one or more of the samples while the sample objects are arranged in the self-organized structure, wherein a measurement on a sample is performed using one or more sensing elements arranged adjacent to the respective sample object in the self-organized structure.